An Analytical Study to evaluate the relationship between Central Obesity and Blood Cholesterol Levels in patients with Periodontal Disease

BACKGROUND: Obesity is a known risk factor for several chronic disease including hypertension, type 2 diabetes, dislipidemoia and coronary heart diseases.(must et al and modad et al 1999). Adipose tissue associated with obesity is known to secrete numerous proinflammatory cytokines such as IL-1 and TNF-α.these proinflammatory cytokines may play a crucial role in the close relationship among obesity, periodontitis and chronic diseases. (beck and offenbecher 2005) AIM OF THE STUDY: The aim of the present study was to determine whether obesity, which is associated with the development of number of chronic diseases, acts as a contributing factor in the development or progression of periodontal disease. MATERIALS AND METHODS: A total of 100 patients was include in the study with age group ranging from 18-59 years. They were divided into the younger 18-34 year olds and the middle aged 35-59 year old subjects. They were further subdivided based upon their BMI. The cutoff value for BMI was 23. Subjects WH ratio was also measured. Venous blood samples were collected for TC, TG, HDL, LDL and HsCRP. Periodontal parameters included were CAL, BI, PD were recorded in full mouth basis at 6 sites per tooth. RESULTS: There was a positive correlation between increasing BMI andWH ratio values with the severity of CAL but the association was not statistically significant. TC, TG, HDL were vwithin the normal limits among the study subjects. There was a significant association between HsCRP in the younger age group whose BMI was 30.97±6.14. CONCLUSION: In this study, there was a positive correlation between indicators of obesity such as BMI and W:H ratio with the severity of periodontal disease but the association was not statistically significant. There may be a weak association between periodontitis and obesity. Further longitudinal studies are required to determine the association between obesity and periodontitis