Hypo glycemic activity of Vellalli Poo Chooranam (Nymphaea alba) and Haematinic activity of Kaandha Chenduram

The test drug “Vellallipoo Chooranam” was selected for the study to establish its efficacy in treating “Madhumegam” Reference were found in Gunapadam Mooligai Vaguppu – Page No – 43. The dose of drug is 1gm b.d daily with lukewarm water before meals. In the review of literature section, Gunapadam Botanical aspects and Phytochemical aspects lateral Research work of trial drug Siddha and Modern aspects of Madhumegam are being discussed and updates from internet have also been added. The Physicochemical analysis indicates the presence of very low acid insoluble ash. The bio-chemical analysis indicates the presence of Ferrous Iron, Amino acid and Tannic acid. Pharmacological analysis shows that this drug has significant Antidiabetic activity microbiological analysis shows that this drug was sensitive of Staphylococcus aureus and streptococcus pneumoniae. Scanning Electron Microscopic study reveals the presence of particles as nanoparticles and it shows trial drug has finished perfectly. Fourier Transform infrared Spectroscopy study reveals the presence of functional group related to Vellallipoo Chooranam. Clinical evaluation of this drug shows good response (77.5%) of patients, fair to response (17.5%) of patients and 5% showed poor response. Bio – stastical analysis also proved that this drug has got highly significant effect in treating madhumegam. No adverse reactions were noted during the treatment. CONCLUSION: It has been concluded that Vellallipoo Chooranam is effective in treating madhumegam without causing any adverse effects