Anti inflammatory Analgesic Anti pyretic Study on Sivakaranthai Ilai Chooranam (Sphaeranthus amaranthoides Burn.f) and Anti Spasmodic and Analgesic study on Venkaram Podi (Sodium tetra borate)

The drug Sivakaranthai ilai was selected for the study to establish the analgesic; anti-inflammatory effect on Azhal keel vayu”. The dose of the Sivakaranthai chooranam is 1 gm twice a day with butter before meals. Brief description in botany regarding the morphological characters of the plant Sivakaranthai was reviewed. From the Gunapadam aspects, various texts, literatures, journals, Internet (Websites) were referred. Bio-chemical analysis was done and it reveals that the drug contains ferrous iron, tannic acid, unsaturated, compound, reducing sugar, amino acid. Microbiological studies revealed that the drug sensitives to Staphylococcus pyogenes Pharmacological studies showed that the drug posses significant analgesic, anti-inflammatory, anti-spasmodic, antipyretic and Antihistamine actions. Clinical studies indicated that the test drug 77.5% patients have good response. Thus, the Anti-inflammatory, Analgesic effect and its role in management of Azhal keel vayu were established in this study. No toxic symptoms or adverse reactions had been appeared during and after the period of treatment. CONCLUSION: This is concluded that the trial drug Sivakaranthai ilai chooranam is found to be an effective in Azhal keelvayu without producing any untoward effects. This study ascertains the activity of this drug as described in siddha literatures