Prospective Randomised Control study on the Effectiveness of Clonidine 1mcg/kg as an Adjuvant to Local Anaesthetic Mixture of 2% Lignocaine with adrenaline and 0.5% Bupivacaine in Supraclavicular Brachial Plexus Block for Providing Post Operative Analgesia in Upper Limb Orthopaedic Surgeries

SUMMARY: This single blinded randomized controlled study was done to evaluate the Onset of motor and sensory blockade, Duration of motor and sensory blockade, Intraoperative hemodynamic changes, Sedation and Side effects of Clonidine used as an adjuvant to the local anesthetic mixture in supraclavicular brachial plexus block for upper limb orthopedic surgeries. The following observations were made: 1. The demographic profiles like Age, Sex, weight, ASA status were comparable in both groups. 2. The onset of motor block occured earlier in Clonidine group than control group. 3. The onset of sensory block occured earlier in Clonidine group than control group. 4. The onset of motor block occured earlier than sensory block in both groups. 5. The hemodynamic parameters like heart rate, systolic blood pressure, diastolic blood pressure, mean arterial pressure were comparable in both the groups. 6. The duration of motor block was longer in Clonidine group than control group. 7. The duration of sensory block was longer in Clonidine group than control group. 8. In Clonidine group, intraoperative sedation was well observed without compromising respiratory functions. 9. There was no significant side effects between the two groups. CONCLUSION: The addition of Clonidine 1μg/kg to local anesthetic mixture in supraclavicular approach to brachial plexus fastens the onset of action of motor and sensory blockade, and prolongs the duration of motor blockade and analgesia significantly without any significant side effects