Study on Role Magnesium Sulphate in Attenuating Succinylcholine induced Fasciculation and Post Operative Myalgia

SUMMARY: From this prospective randomized double blinded study which evaluated the effect of Magnesium sulphate in attenuating Succinylcholine induced muscle fasciculation and post operative myalgia, we found that, 1. The demographic profiles like Age, Sex, weight, ASA PS status are comparable in both the groups. 2. There was 50% reduction in the incidence of muscle fasciculation in the group pretreated with Magnesium sulphate whereas the incidence of fasciculation was 100% in the control group. 3. The incidence of post operative Succinylcholine induced myalgia was 0% in group pretreated with Magnesium sulphate whereas there was 33.30% incidence of post operative myalgia in control group. CONCLUSION: From our study we conclude that MAGNESIUM SULPHATE at a dose of 40mg/kg effectively reduces the Succinylcholine induced muscle fasciculation and Succinylcholine induced post operative myalgia