Lipoprotein (a) estimation in premature coronary artery disease

Significant difference in mean Lipoprotein(a) level was observed between the premature Coronary Artery Disease patients and controls. The mean values of serum Triglycerides, LDL, Total cholesterol, LDL-C, Total-C/HDL-C ratio and LDL-C/HDL-C ratio were found to be higher in premature Coronary Artery Disease patients when compared to controls. In patients with Premature Coronary Artery Disease, higher Lipoprotein(a) levels were observed in female sex, those with family history of Coronary Artery Disease, Smokers, and Diabetics than in male sex, those without family history of Coronary Artery Disease, non-smokers and nondiabetics. There is no significant difference in mean Lipoprotein(a) levels between hypertensives and Normotensives in premature Coronary Artery Disease patients. Higher Lipoprotein(a) levels were observed in all premature Coronary Artery Disease patients with hypercholesterolemia, high LDL levels, low HDL levels and hypertriglyceridemia than those patients with normal serum lipid profile. No significant difference in Lipoprotein(a) levels was observed with respect to age in premature Coronary Artery Disease patients. Alcoholics had lower levels of serum Lipoprotein(a) compared to the Non-alcoholics with coronary artery disease