Neuropharmacological Effects of Methanolic Extract of Leaves of Amaranthus Viridis.L In Rats & Mice

AIM: Now-a-days, there is an increase in demand for herbal drugs due to its safety, efficacy and better therapeutic results and also due to its economic pricing as compared to allopathic drugs. Literature survey has revealed that the plant Amaranthus viridis.L is prescribed in the treatment of diabetes, anti-cholesterolemic, anti-pyretic and anti-nociceptive, hepatoprotective, anti oxidant conditions etc The plant, Amaranthus viridis.L was selected for the present study its, a) Easy availability b) Good therapeutic activity c) Degree of research work which is not done Very less pharmacological studies have been carried out on the plant Amaranthus viridis.L. As per the literature review, so far no scientific study has been carried on this plant Amaranthus viridis.L (Family: Amaranthaceae) to explore the neuroprotective activity. So, the present study has been under taken to explore the neuropharmacological effect of leaves of methanolic extract of leaves of Amaranthus viridis.L which includes studies on pharmacological, Preliminary phytochemical and its pharmacological evaluation. OBJECTIVES: To determine the phytochemical constituents present in the methanolic extract of leaves of A.viridis L., To investigate methanol extracts of leaves of Amaranthus viridis .L (Amaranthaceae) for various neuropharmacological activities, such as anti convulsant, anti depressant and anxiolytic SUMMARY AND CONCLUSION: The present study was undertaken to determine the effect of neuropharmacological effects of leaves of methanolic extract of Amaranthus viridis.L The pharmacognostical studies made on the Amaranthus viridis.L determines the various parameters for pharmacognostical standards. The present investigation deals with the report on microscopically, transverse section of A.viridis leaves of (petiole, midrib, lamina, venation pattern) and different chemical parameters have been determined. These findings will be towards establishing pharmacognostic standards on identification, purity, quality, classification of the plant, which is gaining relevance in plant drug research. The powdered leaves like ash values, extractive values and loss of drying gave valuable information. This helped for correct identification of plant The preliminary phytochemical investigation showed the presence of carbohydrates, alkaloids, steroids and sterols, glycosides, saponins, tannins, flavonoids and phenolic compounds Our conclusion, investigation suggests that methanolic extract of powdered leaves of Amaranthus viridis.L. Which possess potent neuroprotective effects in rats & mice