Evaluation of Antilithiatic Activity of Aqueous Extract of Leaves of Clitoria Ternatea.

The present study evaluated for the possible therapeutic potential of aqueous extract from the leaves of Clitoria ternatea (L) in experimentally induced calcium oxalate urolithic rats and its diuretic potential. The urinary system is the main excretory system and consists of the following structures. 2 kidneys, 2 ureters , Urinary bladder, Urethra. The urinary system plays a vital part in maintaining homeostasis of water and electrolyte concentrations with the body. The kidneys produce urine that contains metabolic waste products, including the nitrogenous compounds urea and uric acid, excess ions and some drugs. CONCLUSION: The presented data about various ion concentrations like calcium, oxalate, magnesium, phosphate excretion in urine analysis and creatinine, uric acid, Blood urea nitrogen (BUN) in serum analysis indicates that the administration of aqueous Extract of Clitoria ternatea leaves to ethylene glycol induced lithiatic rats reduced and prevented the growth of urinary stones, supporting folk information regarding antilithiatic activity of the plant. The mechanism underlying this effect is still unknown, but is apparently related to increased diuresis and lowering of urinary concentrations of stone forming constituents. These finding, thus prompt the necessity for further study to carry out the Mechanism of actions related to antilithiatic effect of Aqueous Extract of Clitoria ternatea leaves. By which more effective treatment for lithiasis can be achieved