Design and Evaluation of Venlafaxine Hydrochloride Sustained Release Matrix Tablet

This study is to check the selected polymer’s sustained drug delivery efficacy. The primary goal of sustained drug delivery system is to reduce dosing frequency and enhance the drug absorption process in a specific manner in order to increase the half-life of the drug. The purpose of this research is to design and develop matrix tablet of Venlafaxine hydrochloride to sustain or control release of drug, which may reduce sudden peak levels of drug in blood In summary, Venlafaxine hydrochlorides higher solubility in water results burst effect with sudden peak levels of drug in blood .By matrix formulation of the drug we can minimize the cost with patient compliance