Study of management of advanced cases of juvenile nasopharyngeal angiofibroma.

Juvenile nasopharyngeal angiofibroma (JNA) is a benign, locally aggressive, highly vascular tumour often occurring at the superior margin of the sphenopalatine foramen occurring exclusively in adolescent males. In this study, 32 cases were analysed. Nasal obstruction and epistaxis were the common symptoms noticed in almost all cases. The likelihood of cure after surgery is approximately 80% to 85%; the probability of ultimate local control approaches 100%. The vast majority of patients have lesions that are completely resectable with relatively limited morbidity and should be treated surgically. A small subset of patients present with recurrent and/or extensive tumours with significant intracranial invasion where the likelihood of complete resection with acceptable morbidity is modest. These patients are best treated with moderate-dose RT