ヒトリンパ芽球とマウス胎児線状体細胞におけるX線及び重粒子線による適応応答誘導に関する研究

  • Guillaume Vares
  • 王 冰
  • 村上 正弘
  • 田中 薫
  • 柿本 彩七
  • 江口−笠井 清美
  • 根井 充
Publication date
February 2019

Abstract

We investigated radiation-induced response to X-rays and heavy-ions in lymphoblastoid cells. As pre-exposure to low priming dose of ionizing radiations decreases the biological effects of a subsequent higher challenging dose in a variety of models, we wondered whether adaptive response could be observed when using accelrated heavy ions radiation. We observed an AR to mutagenic effects of high LET radiation, in relationship with a modulatiion of DNA repair activity.平成19年度放射線医学総合研究所重粒子線がん治療装置等共同利用研究成果発表

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