Search for genetic polymorphisms that associate with radiation-induced normal tissue injury on cancer patients

Conclusion This study implies that analysis of multiple SNPs on adequately selected candidate genes might be specifically suitable for identification of genetic constraints of radiation sensitivity. At present state our findings are still preliminary and require assignment of functional influence of the SNPs to the expression of gene activity that relate to the radiation sensitivity. Our study should encourage further comprehensive search for genetic polymorphisms that associate with radiation-induced normal tissue injury on cancer patients.IAEA Technical Meeting・ESTRO2