Carbon-11-acetate positron emission tomography (PET), versus fluorine-18 fluorodeoxyglucose PET and CT for the diagnosis of recurrent prostate cancer after radical prostatectomy in cases of prostate specific antigen of >1 to 3ng/mL.

Treatment of recurrent prostate cancer (PC) after radical prostatectomy is based on the site of recurrent disease [1-3]. In a previous study, we showed that carbon-11 acetate positron emission tomography (AC PET) demonstrated marked uptake in 27/46 of PC patients in recurrence after radical prostatectomy(RP), while serum PSA was higher than 3.0ng/mL [4]. In the present paper we studied 11 patients with PC following RP, who had no clinical signs of recurrence, with PSA levels of>1.0 or 1.0-3.0ng/mL and under recent hormone treatment