Celiac Disease: Advances in Diagnostic Testing?

• Celiac disease (CD) is a gluten-sensitivity enteropathy that occurs in genetically susceptible individuals upon ingestion of gluten and resolves when gluten is withdrawn from one’s diet. • Serological markers play a major role in the diagnosis of celiac disease, however a small intestinal biopsy is currently the gold standard in symptomatic individuals. • The purpose of this study was to determine if serological testing alone is sufficient to confirm the diagnosis of CD and therefore eliminate the need for a biopsy. • The review of literature explored studies that compared small intestinal biopsy with different serological testing in males and females, \u3c1 to 80 years in age, in order to determine if a biopsy was always necessary.https://commons.und.edu/pas-grad-posters/1134/thumbnail.jp