The dopamine transporter (DAT) is a presynaptic membrane phosphoprotein that terminates dopaminergic synaptic transmission by clearing dopamine (DA) back into presynaptic neuron by a reuptake process. DAT is also a molecular target for psychostimulants such as cocaine, amphetamine (AMPH) and methamphetamine (METH) that increase DA synaptic levels either by blocking reuptake or by inducing DA efflux. DAT phosphorylation and transport down regulation are best demonstrated with the treatment of Protein kinase C (PKC) activators such as (phorbol 12-myristate 13-acetate) PMA. Serine(s) and threonine(s) are known to be involved in DAT phosphorylation. Pretreatment with psychostimulant substrates such as AMPH and METH have been shown to regulate D...
Macrodispersivity estimates are crucial in predicting the subsurface transport of contaminants. Thes...
Parkinson’s disease (PD) is an age-related neurodegenerative disease, which is characterized by the ...
Reported here is a structure activity relationship (SAR) study on a series of mixed efficacy mu opio...
The dopamine transporter (DAT) is a presynaptic membrane phosphoprotein that terminates dopaminergic...
The dopaminergic system is a regulatory system of the brain controlling various motor, cognitive and...
The dopamine transporter (DAT) is a neuronal presynaptic transmembrane protein that clears released ...
The dopamine transporter (DAT) is an integral membrane protein that reuptakes dopamine (DA) from the...
The dopamine (DAT) and serotonin (SERT) transporters are monoamine neurotransmitter transporters (MA...
Chlamydomonas acidophila is a unicellular green alga of the order Chlamydomonadales. Our research ef...
The projects described in this dissertation revolve around the functional consequences experienced b...
Synucleinopathies is the overarching term used to describe a group of neurodegenerative disorders ch...
Tweak and TNF family members are novel regulators of acute and chronic inflammation. Tweak / Fn14 in...
A long-standing postulate holds that cocaine inhibits DAT-mediated dopamine transport via competitio...
Alpha-synuclein (Snca) is a small cytosolic protein that is ubiquitously expressed in the nervous sy...
Masters Degree. University of KwaZulu-Natal, Durban.L-3,4-dihydroxyphenylalanine (L-DOPA) can ease ...
Macrodispersivity estimates are crucial in predicting the subsurface transport of contaminants. Thes...
Parkinson’s disease (PD) is an age-related neurodegenerative disease, which is characterized by the ...
Reported here is a structure activity relationship (SAR) study on a series of mixed efficacy mu opio...
The dopamine transporter (DAT) is a presynaptic membrane phosphoprotein that terminates dopaminergic...
The dopaminergic system is a regulatory system of the brain controlling various motor, cognitive and...
The dopamine transporter (DAT) is a neuronal presynaptic transmembrane protein that clears released ...
The dopamine transporter (DAT) is an integral membrane protein that reuptakes dopamine (DA) from the...
The dopamine (DAT) and serotonin (SERT) transporters are monoamine neurotransmitter transporters (MA...
Chlamydomonas acidophila is a unicellular green alga of the order Chlamydomonadales. Our research ef...
The projects described in this dissertation revolve around the functional consequences experienced b...
Synucleinopathies is the overarching term used to describe a group of neurodegenerative disorders ch...
Tweak and TNF family members are novel regulators of acute and chronic inflammation. Tweak / Fn14 in...
A long-standing postulate holds that cocaine inhibits DAT-mediated dopamine transport via competitio...
Alpha-synuclein (Snca) is a small cytosolic protein that is ubiquitously expressed in the nervous sy...
Masters Degree. University of KwaZulu-Natal, Durban.L-3,4-dihydroxyphenylalanine (L-DOPA) can ease ...
Macrodispersivity estimates are crucial in predicting the subsurface transport of contaminants. Thes...
Parkinson’s disease (PD) is an age-related neurodegenerative disease, which is characterized by the ...
Reported here is a structure activity relationship (SAR) study on a series of mixed efficacy mu opio...