Add to ORKGAntipsychotic medications are effective in the treatment of acute psychosis, irrespective of cause, chronic psychotic disorders, and other psychiatric and non-psychiatric conditions. They are categorized into first-generation antipsychotics (FGAs), also known as “typical” antipsychotics, and second-generation antipsychotics (SGAs), or otherwise known as “atypical” antipsychotics. This review article summarizes both typical and atypical antipsychotics, as well as, examines the mechanism and propensity of these agents to prolong the QTc interval. Keywords: Chlorpromazine, Clozapine, Antipsychotic History, Typical and Atypical Antipsychotics, Psychopharmacotherapy, Psychiatry, QTc, Schizophreni
Typical antipsychotics exert their effect by blocking post-synaptic dopaminergic receptors; blockade...
Introduction: Antipsychotic agents are categorized usually as either “typical antipsychotics” or “at...
Background: Certain psychotropics and a number of other medications used to treat medical conditions...
Antipsychotic medications are the cornerstones of the acute and long-term treatment of schizophreni...
Background: Drug-induced QT prolongation is associated with higher risk of cardiac arrhythmias and c...
INTRODUCTION: Antipsychotic medications are mainstays in the treatment of schizophrenia and a range ...
Background: In psychiatric practice, antipsychotic drugs are widely used group of drugs. Numbers of ...
Objective. We explored the potential association between antipsychotics and QT/QTc duration changes ...
Introduction: The QTc prolongation by antipsychotic drugs is of major concern, especially in light o...
The pharmacological treatment of schizophrenia has made great strides in the last few decades. Many ...
Background: Antipsychotics are frequently used to treat delirium but often induce corrected QT (QTc)...
Objective: Corrected QT (QTc) interval prolongation is often associated with use of first-generation...
Previously, clinicians worked with antipsychotic drugs that almost invariably caused extrapyramidal ...
Background: No clear recommendations exist regarding which antipsychotic drug should be prescribed f...
Background: Many antipsychotic drugs have been associated with QTc prolongation, which is a risk fac...
Typical antipsychotics exert their effect by blocking post-synaptic dopaminergic receptors; blockade...
Introduction: Antipsychotic agents are categorized usually as either “typical antipsychotics” or “at...
Background: Certain psychotropics and a number of other medications used to treat medical conditions...
Antipsychotic medications are the cornerstones of the acute and long-term treatment of schizophreni...
Background: Drug-induced QT prolongation is associated with higher risk of cardiac arrhythmias and c...
INTRODUCTION: Antipsychotic medications are mainstays in the treatment of schizophrenia and a range ...
Background: In psychiatric practice, antipsychotic drugs are widely used group of drugs. Numbers of ...
Objective. We explored the potential association between antipsychotics and QT/QTc duration changes ...
Introduction: The QTc prolongation by antipsychotic drugs is of major concern, especially in light o...
The pharmacological treatment of schizophrenia has made great strides in the last few decades. Many ...
Background: Antipsychotics are frequently used to treat delirium but often induce corrected QT (QTc)...
Objective: Corrected QT (QTc) interval prolongation is often associated with use of first-generation...
Previously, clinicians worked with antipsychotic drugs that almost invariably caused extrapyramidal ...
Background: No clear recommendations exist regarding which antipsychotic drug should be prescribed f...
Background: Many antipsychotic drugs have been associated with QTc prolongation, which is a risk fac...
Typical antipsychotics exert their effect by blocking post-synaptic dopaminergic receptors; blockade...
Introduction: Antipsychotic agents are categorized usually as either “typical antipsychotics” or “at...
Background: Certain psychotropics and a number of other medications used to treat medical conditions...