USE OF PLATELET-RICH FIBRIN IN MAXILLOFACIAL SURGERY

Platelet Rich Fibrin (PRF) is autologous biomaterial which is the second-generation platelet concentrate. It has a favorable biological properties that accelerate healing of soft tissue, and bone, giveing a wide range of applications found in oral and maxillofacial surgery and other surgical fields.PRF technique was developed by Choukroun et al in 2001 and it represents a second generation of autologous platelet concentrate, which is used to accelerate the healing of soft and hard tissue. In contrast to the PRP, the PRF is composed of autologous fibrin matrix in which a large amount of platelets and their growth factors are embedded. PRF-graft is used in augmentative techniques residual bone defects, alone or in combination with biomaterials. When the alveolar ridge augmentation technique GBR, the PRF membranes can be used for protection and stabilization of bone compensation. PRF accelerates the healing of soft tissue and reduces the possibility of dehiscence and exposure of the membrane