A three-dimensional cell-based mechanical model of coronary artery tunica media is proposed. The model is composed of spherical cells forming a hexagonal close-packed lattice. Tissue anisotropy is taken into account by varying interaction forces with the direction of intercellular connection. Several cell-centre interaction potentials for repulsion and attraction are considered, including the Hertz contact model and its neo-Hookean extension, the Johnson–Kendall–Roberts model of adhesive contact, and a wormlike chain model. The model is validated against data from in vitro uni-axial tension tests performed on dissected strips of tunica media. The wormlike chain potential in combination with the neo-Hookean Hertz contact model produces stres...
Detailed morphological data of vascular smooth muscle cells(VSMC) of coronary arteries were limited....
Tissue microstructure, in particular the alignment of myocytes (fibre direction) and their lateral ...
The aim of this study is to elucidate the correlation between coronary artery angulation and local m...
A three-dimensional cell-based mechanical model of coronary artery tunica media is proposed. The mod...
A three-dimensional cell-based mechanical model of coronary artery tunica media is proposed. The mod...
Coronary heart disease is the most frequently occurring cardiovascular disease in Europe. The compon...
Although vascular smooth muscle cells (VSMCs) are pivotal in physiology and pathology, there is a la...
Copyright © 2015 Paul Brocklehurst et al. This is an open access article distributed under the Creat...
Specific cell adhesion is important in cell-mediated immunity, embryogenesis and wound healing. Unde...
A patient-specific mechanical description of the coronary arterial wall is indispensable for individ...
The thesis focuses on investigating cardiac mechanics on a microscale. We consider mechanical proces...
Constitutive models describing the arterial mechanical behavior are important in the development of ...
The mechanical micro-environment within a tissue is linked to phenotypic changes of its constituent ...
The goal of this dissertation is to better understand cellular mechanics across length scales for th...
The aim of this study is to elucidate the correlation between coronary artery angulation and local m...
Detailed morphological data of vascular smooth muscle cells(VSMC) of coronary arteries were limited....
Tissue microstructure, in particular the alignment of myocytes (fibre direction) and their lateral ...
The aim of this study is to elucidate the correlation between coronary artery angulation and local m...
A three-dimensional cell-based mechanical model of coronary artery tunica media is proposed. The mod...
A three-dimensional cell-based mechanical model of coronary artery tunica media is proposed. The mod...
Coronary heart disease is the most frequently occurring cardiovascular disease in Europe. The compon...
Although vascular smooth muscle cells (VSMCs) are pivotal in physiology and pathology, there is a la...
Copyright © 2015 Paul Brocklehurst et al. This is an open access article distributed under the Creat...
Specific cell adhesion is important in cell-mediated immunity, embryogenesis and wound healing. Unde...
A patient-specific mechanical description of the coronary arterial wall is indispensable for individ...
The thesis focuses on investigating cardiac mechanics on a microscale. We consider mechanical proces...
Constitutive models describing the arterial mechanical behavior are important in the development of ...
The mechanical micro-environment within a tissue is linked to phenotypic changes of its constituent ...
The goal of this dissertation is to better understand cellular mechanics across length scales for th...
The aim of this study is to elucidate the correlation between coronary artery angulation and local m...
Detailed morphological data of vascular smooth muscle cells(VSMC) of coronary arteries were limited....
Tissue microstructure, in particular the alignment of myocytes (fibre direction) and their lateral ...
The aim of this study is to elucidate the correlation between coronary artery angulation and local m...