Page 1 contains the nucleotide substitutions observed on each evolved lineage. Page 2 contains a schematic representation of mutations *fixed* on each lineage. Page 3 contains the corresponding amino acid substitutions
<p>A) A cladogram describing the phylogenetic lineage of 52 Pab1 homologues. The numbered nodes alon...
<p>The mutations detected in individual virus mutants are presented. The nucleotide changes observed...
(A) The CYP2D6 sequence is shown together with the location of the substrate recognition site (SRS1-...
<p>For each gene, the nucleotide and amino acid substitutions are shown. Blue and red squares indica...
<p>Summary of the genetic changes specific to the <i>hns</i> mutant lineages.</p
<p>(A) Frequencies of particular nucleotide substitutions within light-chain gene. (B) A graphical v...
<p>The positions of mutations are indicated for regions of the genome in which mutations have been s...
List of base-pair substitutions found in 38 mutation accumulation lines of Wild-type (E. coli PFM2)M...
<p>The nucleotide mutations, corresponding amino acid changes and the frequency of occurrence of mut...
<p>Table of HC and LC point mutation, insertion, and deletion events observed during affinity matura...
Excel file S2. List of de novo mutations in coding regions found in sequenced clones isolated from b...
<p><b>A</b>- Prevalence of mutations in desmosomal genes. <b>B-</b> Prevalence of truncating protein...
List of base-pair substitutions found in 21 mutation accumulation lines of Wild-type 6K (E. coli PFM...
<p>Table showing mutagen used, coding sequence change, type of mutation, and resulting effective ami...
<p>Schematic representation of the mutations found in CVI passage isolates. The number of amino acid...
<p>A) A cladogram describing the phylogenetic lineage of 52 Pab1 homologues. The numbered nodes alon...
<p>The mutations detected in individual virus mutants are presented. The nucleotide changes observed...
(A) The CYP2D6 sequence is shown together with the location of the substrate recognition site (SRS1-...
<p>For each gene, the nucleotide and amino acid substitutions are shown. Blue and red squares indica...
<p>Summary of the genetic changes specific to the <i>hns</i> mutant lineages.</p
<p>(A) Frequencies of particular nucleotide substitutions within light-chain gene. (B) A graphical v...
<p>The positions of mutations are indicated for regions of the genome in which mutations have been s...
List of base-pair substitutions found in 38 mutation accumulation lines of Wild-type (E. coli PFM2)M...
<p>The nucleotide mutations, corresponding amino acid changes and the frequency of occurrence of mut...
<p>Table of HC and LC point mutation, insertion, and deletion events observed during affinity matura...
Excel file S2. List of de novo mutations in coding regions found in sequenced clones isolated from b...
<p><b>A</b>- Prevalence of mutations in desmosomal genes. <b>B-</b> Prevalence of truncating protein...
List of base-pair substitutions found in 21 mutation accumulation lines of Wild-type 6K (E. coli PFM...
<p>Table showing mutagen used, coding sequence change, type of mutation, and resulting effective ami...
<p>Schematic representation of the mutations found in CVI passage isolates. The number of amino acid...
<p>A) A cladogram describing the phylogenetic lineage of 52 Pab1 homologues. The numbered nodes alon...
<p>The mutations detected in individual virus mutants are presented. The nucleotide changes observed...
(A) The CYP2D6 sequence is shown together with the location of the substrate recognition site (SRS1-...
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