The effect of unmodified stroma reduced (SRHb) and modified diaspirin crosslinked (DCLHbâ„¢) hemoglobin solutions on the mean arterial pressure and endothelin-1 (ET-1) concentration in blood plasma and various tissues was studied. Infusion of DCLHb or SRHb increased mean arterial blood pressure by 96 % and 39 %, respectively. Heart rate was not significantly affected by DCLHb or SRHb. A significant increase (P \u3c 0.003) in the ET-1 levels in blood plasma after DCLHb and SRHb infusion was observed. The increase in plasma ET-1 concentration was significantly more marked with SRHb (141 %) as compared to DCLHb (78 %) treated rats. The concentration of ET-1 in the heart and brain regions was not altered in DCLHb and SRHb treated rats as compar...
The present thesis examined the role of endothelin-1 (ET-1), a potent 21-aminoacid vasoconstrictor-...
Endothelin, a 21-amino-acid peptide, binds to a specific receptor on vascular smooth muscle cells, t...
Endothelin, a 21-amino-acid peptide, binds to a specific receptor on vascular smooth muscle cells, t...
Objectives: Diaspirin crosslinked hemoglobin is a resuscitative solution with excellent oxygen-carry...
Diaspirin cross-linked hemoglobin (DCLHb(®)) (Baxter Healthcare Corporation) is a promising resusci...
Objective: Diaspirin crosslinked hemoglobin, a hemoglobin-based blood substitute, is proposed to be ...
Diaspirin cross-linked hemoglobin (DCLHb) is a hemo-globin-based therapeutic agent that produces sig...
The role of nitric oxide (NO) in the cardiovascular actions of diaspirin cross-linked hemoglobin (DC...
Previous studies have demonstrated that endothelin-1 (ET-1) is a potent vasoconstrictor that decreas...
There are interactions between endothelin-1 (ET-1) and endothelial vascular injury in hyperhomocyste...
Endothelin-1 (1-31) (ET-1 (1-31)) is a novel member of the endothelin family, which comprises 31 ami...
There are interactions between endothelin-1 (ET-1) and endothelial vascular injury in hyperhomocyste...
Abstract We have previously shewn that the endothelin content in arteries of deoxycorticosterone ace...
There are interactions between endothelin-1 (ET-1) and endothelial vascular injury in hyperhomocyste...
The present thesis examined the role of endothelin-1 (ET-1), a potent 21-aminoacid vasoconstrictor-...
The present thesis examined the role of endothelin-1 (ET-1), a potent 21-aminoacid vasoconstrictor-...
Endothelin, a 21-amino-acid peptide, binds to a specific receptor on vascular smooth muscle cells, t...
Endothelin, a 21-amino-acid peptide, binds to a specific receptor on vascular smooth muscle cells, t...
Objectives: Diaspirin crosslinked hemoglobin is a resuscitative solution with excellent oxygen-carry...
Diaspirin cross-linked hemoglobin (DCLHb(®)) (Baxter Healthcare Corporation) is a promising resusci...
Objective: Diaspirin crosslinked hemoglobin, a hemoglobin-based blood substitute, is proposed to be ...
Diaspirin cross-linked hemoglobin (DCLHb) is a hemo-globin-based therapeutic agent that produces sig...
The role of nitric oxide (NO) in the cardiovascular actions of diaspirin cross-linked hemoglobin (DC...
Previous studies have demonstrated that endothelin-1 (ET-1) is a potent vasoconstrictor that decreas...
There are interactions between endothelin-1 (ET-1) and endothelial vascular injury in hyperhomocyste...
Endothelin-1 (1-31) (ET-1 (1-31)) is a novel member of the endothelin family, which comprises 31 ami...
There are interactions between endothelin-1 (ET-1) and endothelial vascular injury in hyperhomocyste...
Abstract We have previously shewn that the endothelin content in arteries of deoxycorticosterone ace...
There are interactions between endothelin-1 (ET-1) and endothelial vascular injury in hyperhomocyste...
The present thesis examined the role of endothelin-1 (ET-1), a potent 21-aminoacid vasoconstrictor-...
The present thesis examined the role of endothelin-1 (ET-1), a potent 21-aminoacid vasoconstrictor-...
Endothelin, a 21-amino-acid peptide, binds to a specific receptor on vascular smooth muscle cells, t...
Endothelin, a 21-amino-acid peptide, binds to a specific receptor on vascular smooth muscle cells, t...