Background: One of the most common difficulties found in leprosy management is how to manage leprosy reaction, even though MDT has proven to be effective for the patients. Reversal reaction is associated with cell mediated immunity (CMI), consists of T-helper (Th) 1 and Th2 activities. Moreover, subset of CD4+ Th17 and CD25+ FOXP3 Treg were known to have an important role in leprosy’s natural history. Prior study showed a decreasing number of CD25+ FOXP3 Treg and increasing number of CD4+ Th17 in type II reversal reaction (ENL). However, the distribution of Th17 and Treg in type I reversal reaction (RR) has not yet been identified.Objective: To compare the distribution of CD4+ Th17 and CD25+ FOXP3 Treg between RR and ENL patient groups.Meth...
BackgroundLeprosy is a treatable infectious disease caused by Mycobacterium leprae. However, there i...
Background: Reversal reaction (RR) is an acute reaction on chronic episode which often contributes t...
Patients with localized tuberculoid and generalized lepromatous leprosy show respectively Th1 and Th...
Background: One of the most common difficulties found in leprosy management is how to manage leprosy...
BACKGROUND: Leprosy is characterized histologically by a spectrum of different granul...
Leprosy is a complex chronic, infectious dermato-neurological disease that affects the skin and peri...
Leprosy is a disease caused by Mycobacterium leprae where the clinical spectrum correlates with the ...
BACKGROUND: The numbers of circulating regulatory T cells (Tregs) are increased in lepromatous lepro...
T cell defect is a common feature in lepromatous or borderline lepromatous leprosy (LL/BL) patients ...
Background: Patients with localized tuberculoid and generalized lepromatous leprosy show respectivel...
Background: Lepromatous leprosy caused by Mycobacterium leprae is associated with antigen specific T...
<div><p>Leprosy is a disease caused by Mycobacterium leprae where the clinical spectrum correlates w...
Leprosy is a disease caused by Mycobacterium leprae, an acid-fast bacillus whose clinical spectrum c...
T regulatory cells (Tregs) play an important role in the mechanism of host's failure to control path...
Leprosy is a disease caused by Mycobacterium leprae where the clinical spectrum correlates with the ...
BackgroundLeprosy is a treatable infectious disease caused by Mycobacterium leprae. However, there i...
Background: Reversal reaction (RR) is an acute reaction on chronic episode which often contributes t...
Patients with localized tuberculoid and generalized lepromatous leprosy show respectively Th1 and Th...
Background: One of the most common difficulties found in leprosy management is how to manage leprosy...
BACKGROUND: Leprosy is characterized histologically by a spectrum of different granul...
Leprosy is a complex chronic, infectious dermato-neurological disease that affects the skin and peri...
Leprosy is a disease caused by Mycobacterium leprae where the clinical spectrum correlates with the ...
BACKGROUND: The numbers of circulating regulatory T cells (Tregs) are increased in lepromatous lepro...
T cell defect is a common feature in lepromatous or borderline lepromatous leprosy (LL/BL) patients ...
Background: Patients with localized tuberculoid and generalized lepromatous leprosy show respectivel...
Background: Lepromatous leprosy caused by Mycobacterium leprae is associated with antigen specific T...
<div><p>Leprosy is a disease caused by Mycobacterium leprae where the clinical spectrum correlates w...
Leprosy is a disease caused by Mycobacterium leprae, an acid-fast bacillus whose clinical spectrum c...
T regulatory cells (Tregs) play an important role in the mechanism of host's failure to control path...
Leprosy is a disease caused by Mycobacterium leprae where the clinical spectrum correlates with the ...
BackgroundLeprosy is a treatable infectious disease caused by Mycobacterium leprae. However, there i...
Background: Reversal reaction (RR) is an acute reaction on chronic episode which often contributes t...
Patients with localized tuberculoid and generalized lepromatous leprosy show respectively Th1 and Th...