Keratoconus: Clinical Associations and Treatment Options

The focus of the present review of literature is keratoconus, a progressive thinning of the cornea. Because keratoconus usually induces irregular astigmatism, the most affected patients experience a decreased visual acuity that limits the correction using ophthalmic lenses. The CLEK (Collaborative Longitudinal Evaluation of Keratoconus) is a study carried out in several centers with the aim of describing the evolution and associations between the visual and physiological manifestations of keratoconus. Since the treatment of keratoconus varies according to its severity, this paper proposes a summary of the results of the CLEK and a review of the therapeutic options