Brain cell death is reduced with cooling by 3.5°C to 5°C but increased with cooling by 8.5°C in a piglet asphyxia model.
- Alonso-Alconada, Daniel
- Broad, Kevin D
- Bainbridge, Alan
- Chandrasekaran, Manigandan
- Faulkner, Stuart
- Kerenyi, Áron
- Hassell, Jane
- Rocha-Ferreira, Eridan
- Hristova, Mariya
- Fleiss, Bobbi
- Bennett, Kate
- Kelen, Dorottya
- Cady, Ernest
- Gressens, Pierre
- Golay, Xavier
- Robertson, Nicola NJ
Publication date
January 2015
DOI Publisher
Ovid Technologies (Wolters Kluwer Health)Abstract
In infants with moderate to severe neonatal encephalopathy, whole-body cooling at 33°C to 34°C for 72 hours is standard care with a number needed to treat to prevent a adverse outcome of 6 to 7. The precise brain temperature providing optimal neuroprotection is unknown.info:eu-repo/semantics/publishe
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