Add to ORKGFive strains of mice were used in metabolic studies measuring oxygen consumption to determine if aging rates were affected according to the free radical theory of aging. The strains were the C57BL/6, DBA/2J, B6D2F1, B6 OB/OB, AND BALB/cJ. Oxygen consumption was higher in all strains, except the BALB strain, in the mice that were food restricted. This refutes the theory that food restriction reduces metabolic rate thus lowering oxygen consumption. Possible explanations are included
Two theories of how energy metabolism should be associated with longevity, both mediated via free-ra...
Abstract A negative association between resting meta-bolic rate (RMR) and lifespan is the cornerston...
<p>(<b>A</b>) Oxygen consumption in isolated mitochondria was measured using an oxygen electrode cuv...
The hypothesis, that a decrease in metabolic rate mediates the life span prolonging effect of calori...
Growth hormone signaling influences longevity but the mechanism through which decreased GH action ex...
Indirect calorimetry (InCa) can potentially be used to noninvasively assess metabolic and age-relate...
Lifelong food restriction to two-thirds of normal ad libitum consumption extended mean and maximum l...
The proposition that increased energy expenditure shortens life has a long history. The rate-of-livi...
Reducing the intake of dietary energy by laboratory rodents to well below that of animals allowed to...
The effects of dietary free radical inhibitors and of feed restriction on selected age associated bi...
Restricted feeding of rodents increases longevity, but its mechanism of action is not understood. We...
Glucose metabolism is altered in long-lived people and mice. Although it is clear that there is an a...
That one or multiple measures of metabolic rate may be robustly associated with, or possibly even ca...
Dietary restriction (DR) across a wide phylogenetic range increases both mean and maximal lifespan b...
Individual differences in the rate of aging are determined by the efficiency with which an organism ...
Two theories of how energy metabolism should be associated with longevity, both mediated via free-ra...
Abstract A negative association between resting meta-bolic rate (RMR) and lifespan is the cornerston...
<p>(<b>A</b>) Oxygen consumption in isolated mitochondria was measured using an oxygen electrode cuv...
The hypothesis, that a decrease in metabolic rate mediates the life span prolonging effect of calori...
Growth hormone signaling influences longevity but the mechanism through which decreased GH action ex...
Indirect calorimetry (InCa) can potentially be used to noninvasively assess metabolic and age-relate...
Lifelong food restriction to two-thirds of normal ad libitum consumption extended mean and maximum l...
The proposition that increased energy expenditure shortens life has a long history. The rate-of-livi...
Reducing the intake of dietary energy by laboratory rodents to well below that of animals allowed to...
The effects of dietary free radical inhibitors and of feed restriction on selected age associated bi...
Restricted feeding of rodents increases longevity, but its mechanism of action is not understood. We...
Glucose metabolism is altered in long-lived people and mice. Although it is clear that there is an a...
That one or multiple measures of metabolic rate may be robustly associated with, or possibly even ca...
Dietary restriction (DR) across a wide phylogenetic range increases both mean and maximal lifespan b...
Individual differences in the rate of aging are determined by the efficiency with which an organism ...
Two theories of how energy metabolism should be associated with longevity, both mediated via free-ra...
Abstract A negative association between resting meta-bolic rate (RMR) and lifespan is the cornerston...
<p>(<b>A</b>) Oxygen consumption in isolated mitochondria was measured using an oxygen electrode cuv...