Drug therapy problems in the hospitalized patients identified during the pre-registration training for pharmacists

Cilj istraživanja: Cilj ovog rada bio je analizirati terapijske probleme prikupljene tijekom stručnog osposobljavanja studenata pete godine Farmaceutsko-biokemijskog fakulteta Sveučilišta u Zagrebu. Ispitanici i metode: Studenti su podatke o bolesnicima prikupili u razdoblju od 2016. do 2018. godine, a uključivali su osnovne podatke o bolesniku, povijest bolesti, adherenciju, propisane lijekove prije prijema i tijekom hospitalizacije, laboratorijske pretrage te identificirane terapijske probleme. Alat za definiranje terapijskih problema preuzet je od Cipolle i sur. (2012). Određena je učestalost pojedinih terapijskih problema te udio prepoznatih terapijskih problema od strane studenata. Rezultati: U istraživanje je bilo uključeno 72 studenta koji su prikupili podatke od 75 bolesnika. Bolesnici su bili prosječne životne dobi 65,5 godina (raspon 41 – 88). Medijan komorbiditeta iznosio je 6 (raspon 2 – 14), a korištenih lijekova 10 (raspon 3 – 20). Svaki bolesnik imao je barem jedan terapijski problem, prosječna vrijednost iznosila je 5,8 2,9, a najveći broj bolesnika (n=15; 20 %) imao je 4 terapijska problema. Studenti su utvrdili 47,2 % terapijskih problema. Najučestaliji uzrok terapijskih problema bila je nuspojava lijeka (n=110; 25,2 %; studenti n=46; 22,3 %), a zatim previsoka doza (n=81, 18,6 %; studenti n=43; 20,9 %). Zaključak: Ovaj rad je utvrdio da su studenti prepoznali velik broj terapijskih problem, iako još uvijek nedovoljan. Rezultati potvrđuju da je važno razvijati vještinu prepoznavanja terapijskih problema još za vrijeme studija kako bi osigurali razvoj kompetentnih stručnjaka koji će u budućnosti odgovornim pružanjem ljekarničke skrbi doprinijeti pozitivnim ishodima liječenja.Objectives: The aim of this study was to analyse drug therapy problems of hospitalized patients identified during the pre-registration training of the fifth-year students of the Faculty of Pharmacy and Biochemistry, University of Zagreb. Subjects and methods: Students collected patient data in the period from 2016. to 2018. Data included basic patient information, comorbidities, adherence, medication history prior to hospitalization, prescribed medicines during the hospitalization and laboratory tests. Drug therapy problems were evaluated according to Cipolle et al. classification (2012). Results: There were 72 students included in the study who collected data from 75 patient. The median of patients' age was 65,5 years (range 41 – 88), and patients presented with median of 6 comorbidities (range 2 – 14), and 10 medications (range 3 – 20). Every patient had at least one drug related problem, while on average 5,8 2,9 drug related problems per patient were identified. The largest proportion of patients (n=15; 20 %) had 4 drug related problems. Students detected 47,2 % of the drug related problems. The most common causes of drug related problems were adverse drug reactions (n=110, 25,2 %, students n=46, 22,3 %) and dose being too high (n=81, 18,6 %; students n=43, 20,9 %). Conclusion: Although students identified large number of drug therapy problems, we perceived the need for the improvement. This work emphasizes the importance of developing skills for drug therapy problems identification during the undergraduate studies. We believe that empowering students with such skills could ensure the development of professionals competent for pharmaceutical care provision and could greatly contribute to the positive outcomes of the treatment