CRAE Training Reduces Insulin Resistance and Central Adiposity in Obese Adolescent Females

CRAE Training Reduces Insulin Resistance and Central Adiposity in Obese Adolescent Females Rebecca Cuthbert, Leena P Bharath, William W Choi, Jae-min Cho, Alexus A Skobodzinski, Alexei Wong, Ty E Sweeney, Dustin Slivka, Song-Young Park University of Nebraska at Omaha, Omaha, Nebraska Exercise training is recommended for maintaining health and reducing the risks of developing metabolic and cardiovascular pathologies. Combined resistance and aerobic exercise (CRAE) training has been utilized to decrease metabolic risk factors in obese adults. PURPOSE: To determine the effects of CRAE on obese adolescent females with hyperinsulinemia. METHODS: Forty obese adolescent females aged 14.7 ± 1 years (BMI 30 ± 2 kg/m2) were randomly assigned to the exercise group (EX, n = 20) or the control group (CON, n = 20). The EX group performed CRAE 5 days a week for 12 weeks. The intensity gradually increased by 10% every 4 weeks, from 40 – 70% of their heart rate reserve (HRR). Body composition, blood pressure (BP), heart rate (HR), brachial-ankle pulse wave velocity (BaPWV), blood leptin, adiponectin, glucose, and insulin were measured pre- and post-training. RESULTS: CRAE reduced the body fat percentage, body weight, and waist circumference of the EX group (p \u3c 0.05) compared to the CON group after 12 weeks of testing. EX maintained appropriate levels of blood leptin and adiponectin while their insulin, glucose, and insulin resistant parameters decreased compared to their baseline and the control group (p \u3c 0.05). CONCLUSION: These data show that CRAE is a safe and useful therapeutic method to improve metabolic risk factors of obese adolescent females with hyperinsulinemia