Add to ORKGBackground: Cardiovascular disease, diabetes, and kidney disease are among the leading causes of death and disability worldwide. However, knowledge of genetic determinants of those diseases in African Americans remains limited. Results: In our study, associations between 4956 GWAS catalog reported SNPs and 67 traits were examined among 7726 African Americans from the REasons for Geographic and Racial Differences in Stroke (REGARDS) study, which is focused on identifying factors that increase stroke risk. The prevalent and incident phenotypes studied included inflammation, kidney traits, cardiovascular traits and cognition. Our results validated 29 known associations, of which eight associations were reported for the first time in African Am...
Background Coronary heart disease (CHD) is a leading cause of morbidity and mortality in African Ame...
OBJECTIVES: To evaluate the association of genetic variation with late-onset Alzheimer disease (AD) ...
African Americans are disproportionately affected by type 2 diabetes (T2DM) yet few studies have exa...
Background: Cardiovascular disease, diabetes, and kidney disease are among the leading causes of dea...
BACKGROUND: Cardiovascular disease, diabetes, and kidney disease are among the leading causes of ...
Background and purposeThe majority of genome-wide association studies (GWAS) of stroke have focused ...
We performed a hypothesis-generating phenome-wide association study (PheWAS) to identify and charact...
African Americans have the highest rate of mortality due to coronary heart disease (CHD). Although m...
Using data from four community-based cohorts of African Americans (AA), we tested the association be...
Coronary heart disease (CHD) is the leading cause of mortality in African Americans. To identify com...
Background and Purpose: Stroke is a complex disease with multiple genetic and environmental risk fac...
BACKGROUND AND PURPOSE: Stroke is a complex disease with multiple genetic and environmental risk fac...
Background: African Americans (AAs) suffer a higher stroke burden due to hypertension. Identifying g...
poster abstractSince the completion of the Human Genome Project, it has been found that genes and th...
BACKGROUND: Genome-wide association studies (GWAS) have identified loci associated with ischemic str...
Background Coronary heart disease (CHD) is a leading cause of morbidity and mortality in African Ame...
OBJECTIVES: To evaluate the association of genetic variation with late-onset Alzheimer disease (AD) ...
African Americans are disproportionately affected by type 2 diabetes (T2DM) yet few studies have exa...
Background: Cardiovascular disease, diabetes, and kidney disease are among the leading causes of dea...
BACKGROUND: Cardiovascular disease, diabetes, and kidney disease are among the leading causes of ...
Background and purposeThe majority of genome-wide association studies (GWAS) of stroke have focused ...
We performed a hypothesis-generating phenome-wide association study (PheWAS) to identify and charact...
African Americans have the highest rate of mortality due to coronary heart disease (CHD). Although m...
Using data from four community-based cohorts of African Americans (AA), we tested the association be...
Coronary heart disease (CHD) is the leading cause of mortality in African Americans. To identify com...
Background and Purpose: Stroke is a complex disease with multiple genetic and environmental risk fac...
BACKGROUND AND PURPOSE: Stroke is a complex disease with multiple genetic and environmental risk fac...
Background: African Americans (AAs) suffer a higher stroke burden due to hypertension. Identifying g...
poster abstractSince the completion of the Human Genome Project, it has been found that genes and th...
BACKGROUND: Genome-wide association studies (GWAS) have identified loci associated with ischemic str...
Background Coronary heart disease (CHD) is a leading cause of morbidity and mortality in African Ame...
OBJECTIVES: To evaluate the association of genetic variation with late-onset Alzheimer disease (AD) ...
African Americans are disproportionately affected by type 2 diabetes (T2DM) yet few studies have exa...