Modern computer software systems are complicated. Developers can change the behavior of the software system through software configurations. The large number of configuration option and their interactions make the task of software tuning, testing, and debugging very challenging. Performance is one of the key aspects of non-functional qualities, where performance bugs can cause significant performance degradation and lead to poor user experience. However, performance bugs are difficult to expose, primarily because detecting them requires specific inputs, as well as specific configurations. While researchers have developed techniques to analyze, quantify, detect, and fix performance bugs, many of these techniques are not effective in highly-c...