Add to ORKGProvided are bis-quaternary ammonium compounds which are modulators of nicotinic acetylcholine receptors. Also provided are methods of using the compounds for modulating the function of a nicotinic acetylcholine receptor, and for the prevention and/or treatment of central nervous system disorders, substance use and/or abuse, and or gastrointestinal tract disorders
Compounds used for treating dependence on or withdrawal from a drug of abuse, for an eating disorder...
This project utilized synthesis and in vitro assays to generate antagonist SARs at various nAChR sub...
Photoactivatable pharmacological agents have revolutionized neuroscience, but the palette of availab...
Provided are bis-quaternary ammonium compounds which are modulators of nicotinic acetylcholine recep...
Provided are monoquaternary ammonium compounds which are modulators of nicotinic acetylcholine recep...
Provided are tetrakis-quaternary ammonium compounds which are modulators of nicotinic acetylcholine ...
Provided are tris-quaternary ammonium compounds which are modulators of nicotinic acetylocholine rec...
Provided are bis-quaternary ammonium cyclophane compounds which are modulators of nicotinic acetylch...
Provided are methods for using his-quaternary ammonium compounds to treat inflammatory pain, neuropa...
Provided are tris-quatemary ammonium compounds which are modulators of nociception and pain
Nicotine analogs that have nicotinic receptor antagonist properties. These compounds have been shown...
Compounds for treating abuse of nicotinic receptor agonists, addiction to psychostimulant drugs, add...
N-n-Alkylation of nicotine converts nicotine from an agonist into an antagonist specifically for neu...
Pharmaceutical compounds comprising bridged nicotine analogs of N-octylnicotinium iodide (NONI) havi...
Provided are methods for using bis-quaternary ammonium compounds to treat inflammatory pain, neuropa...
Compounds used for treating dependence on or withdrawal from a drug of abuse, for an eating disorder...
This project utilized synthesis and in vitro assays to generate antagonist SARs at various nAChR sub...
Photoactivatable pharmacological agents have revolutionized neuroscience, but the palette of availab...
Provided are bis-quaternary ammonium compounds which are modulators of nicotinic acetylcholine recep...
Provided are monoquaternary ammonium compounds which are modulators of nicotinic acetylcholine recep...
Provided are tetrakis-quaternary ammonium compounds which are modulators of nicotinic acetylcholine ...
Provided are tris-quaternary ammonium compounds which are modulators of nicotinic acetylocholine rec...
Provided are bis-quaternary ammonium cyclophane compounds which are modulators of nicotinic acetylch...
Provided are methods for using his-quaternary ammonium compounds to treat inflammatory pain, neuropa...
Provided are tris-quatemary ammonium compounds which are modulators of nociception and pain
Nicotine analogs that have nicotinic receptor antagonist properties. These compounds have been shown...
Compounds for treating abuse of nicotinic receptor agonists, addiction to psychostimulant drugs, add...
N-n-Alkylation of nicotine converts nicotine from an agonist into an antagonist specifically for neu...
Pharmaceutical compounds comprising bridged nicotine analogs of N-octylnicotinium iodide (NONI) havi...
Provided are methods for using bis-quaternary ammonium compounds to treat inflammatory pain, neuropa...
Compounds used for treating dependence on or withdrawal from a drug of abuse, for an eating disorder...
This project utilized synthesis and in vitro assays to generate antagonist SARs at various nAChR sub...
Photoactivatable pharmacological agents have revolutionized neuroscience, but the palette of availab...