This invention relates to amino acid derivatives that are useful as inhibitors of bacterial collagenase. . . To read the remainder of this abstract, please download this patent
The glycoproteins of selected microbial pathogens often include highly modified carbohydrates such a...
Compounds containg catechol or bisphosphonate were tested as inhibitors of the zinc metalloproteases...
Collagens are a major constituent of the extracellular matrices of many biological tissues. Their st...
Bacterial virulence factors are mediating bacterial pathogenesis and infectivity. Collagenases are v...
From Introduction: Collagenases are enzymes capable of specifically attacking the native collagen he...
Despite the progress in surgical techniques and antibiotic prophylaxis, opportunistic wound infectio...
Accumulation of collagen is the major pathologic feature in a variety of fibrotic processes, includi...
Secreted virulence factors like bacterial collagenases are conceptually attractive targets for fight...
In view of the worldwide antimicrobial resistance (AMR) threat, new bacterial targets and anti-infe...
The pharmacological inhibition of the bacterial collagenases (BC) enzymes is considered a promising ...
Thesis (Ph.D.)--Boston UniversityThe purpose of the research described in this thesis was to determi...
As resistance to clinically available antibiotics persistently increases, applying new strategies to...
Secreted virulence factors like bacterial collagenases are conceptually attractive targets for fight...
There is an urgent need for the development of new therapeutics with novel modes of action to target...
AbstractNon-invasive therapeutic methods have recently been used in medical sciences. Enzymes have s...
The glycoproteins of selected microbial pathogens often include highly modified carbohydrates such a...
Compounds containg catechol or bisphosphonate were tested as inhibitors of the zinc metalloproteases...
Collagens are a major constituent of the extracellular matrices of many biological tissues. Their st...
Bacterial virulence factors are mediating bacterial pathogenesis and infectivity. Collagenases are v...
From Introduction: Collagenases are enzymes capable of specifically attacking the native collagen he...
Despite the progress in surgical techniques and antibiotic prophylaxis, opportunistic wound infectio...
Accumulation of collagen is the major pathologic feature in a variety of fibrotic processes, includi...
Secreted virulence factors like bacterial collagenases are conceptually attractive targets for fight...
In view of the worldwide antimicrobial resistance (AMR) threat, new bacterial targets and anti-infe...
The pharmacological inhibition of the bacterial collagenases (BC) enzymes is considered a promising ...
Thesis (Ph.D.)--Boston UniversityThe purpose of the research described in this thesis was to determi...
As resistance to clinically available antibiotics persistently increases, applying new strategies to...
Secreted virulence factors like bacterial collagenases are conceptually attractive targets for fight...
There is an urgent need for the development of new therapeutics with novel modes of action to target...
AbstractNon-invasive therapeutic methods have recently been used in medical sciences. Enzymes have s...
The glycoproteins of selected microbial pathogens often include highly modified carbohydrates such a...
Compounds containg catechol or bisphosphonate were tested as inhibitors of the zinc metalloproteases...
Collagens are a major constituent of the extracellular matrices of many biological tissues. Their st...