Add to ORKGProdrugs containing an active drug molecule linked to a polyethylene glycol group, and a method of use thereof are described. Exemplary soluble ester prodrugs contain naproxen, triamcinolone acetonide, gancyclovir, taxol, cyclosporin, dideoxyinosine, trihydroxy steroids, and flurbiprofen molecules linked to polyethylene glycol (PEG) groups. Pharmaceutical compositions containing these prodrugs, and a method of using these esters for treating disease states or symptoms are also described
Mono- and di-iodinated nonoxynol-9-derivatives and methods for their use are disclosed
Eugenol (EU) and ibuprofene (IBU) were covalently bound to a bi-functionalized PEG, used as molecula...
A small library of polyethylene glycol esters of Palmitoylethanolamide (PEA) was synthesized with th...
Prodrugs containing an active drug molecule linked to a polyethylene glycol group, and a method of u...
The present invention relates to the field of prodrugs of chemotherapeutic agents and method of use ...
The presently-disclosed subject matter includes compounds including a cyclooxygenase enzyme inhibito...
A codrug composition of at least two drug compounds covalently linked to one another via a labile bo...
A composition, a method and an apparatus for transdermally delivering an effective amount of opioid ...
The present invention relates to novel intermediates and prodrugs of camptothecin and related analog...
The design and the synthesis of prodrugs for nonsteroidal anti-inflammatory drugs (NSAIDs) have been...
Prodrugs or predrugs are inactive molecules which become active after in vivo conversion to release ...
Prodrugs are chemically modified derivatives introduced in therapy due to their advantageous physico...
The present invention relates to novel, highly lipophilic silatecan intermediates and prodrugs of DB...
The present study was divided between two different drug delivery goals, each involving naltrexone (...
AbstractThe current work envisages synthesis of an ester prodrug of flurbiprofen whereby its carboxy...
Mono- and di-iodinated nonoxynol-9-derivatives and methods for their use are disclosed
Eugenol (EU) and ibuprofene (IBU) were covalently bound to a bi-functionalized PEG, used as molecula...
A small library of polyethylene glycol esters of Palmitoylethanolamide (PEA) was synthesized with th...
Prodrugs containing an active drug molecule linked to a polyethylene glycol group, and a method of u...
The present invention relates to the field of prodrugs of chemotherapeutic agents and method of use ...
The presently-disclosed subject matter includes compounds including a cyclooxygenase enzyme inhibito...
A codrug composition of at least two drug compounds covalently linked to one another via a labile bo...
A composition, a method and an apparatus for transdermally delivering an effective amount of opioid ...
The present invention relates to novel intermediates and prodrugs of camptothecin and related analog...
The design and the synthesis of prodrugs for nonsteroidal anti-inflammatory drugs (NSAIDs) have been...
Prodrugs or predrugs are inactive molecules which become active after in vivo conversion to release ...
Prodrugs are chemically modified derivatives introduced in therapy due to their advantageous physico...
The present invention relates to novel, highly lipophilic silatecan intermediates and prodrugs of DB...
The present study was divided between two different drug delivery goals, each involving naltrexone (...
AbstractThe current work envisages synthesis of an ester prodrug of flurbiprofen whereby its carboxy...
Mono- and di-iodinated nonoxynol-9-derivatives and methods for their use are disclosed
Eugenol (EU) and ibuprofene (IBU) were covalently bound to a bi-functionalized PEG, used as molecula...
A small library of polyethylene glycol esters of Palmitoylethanolamide (PEA) was synthesized with th...