A composition, a method and an apparatus for transdermally delivering an effective amount of opioid antagonists derived from prodrugs for treatment of eating disorders, narcotic dependence and alcoholism. In addition, the present invention relates to a composition, a method and an apparatus for transdermally delivering an effective amount of an opioid and opioid antagonist derived from an opioid agonist and one of an opioid antagonist and a prodrug for treatment of pain
The adequate treatment of pain remains one of the major medical challenges. Morphine and other opioi...
Patients with a history of abuse/misuse of pain and psychotic medications are at high risk for suici...
Putting into service a preliminary transdermal patch on the skin, an appropriate dosage of drug can ...
A pharmaceutical composition comprising a phosphatidylcholine-based opioid receptor antagonist formu...
Improved pharmacotherapies for opioid dependence treatment have become a necessity for maintaining i...
The invention provides compounds of formula I: wherein R1 to R4 and n have any of the meanings defin...
Particles comprising an opioid receptor antagonist as well as methods of their use and methods of th...
ABSTRACTOpioid continues as the main pharmacological treatment for severe acute pain. Extensive firs...
The present invention relates to the field of prodrugs of chemotherapeutic agents and method of use ...
The present invention relates to pharmaceutical compositions for intranasal administration to a mamm...
Novel compounds which selectively bind to the δ-opioid receptor have been designed. These compounds ...
Several investigations into the sites of action of opioid analgesics have utilized peripherally acti...
Prodrugs containing an active drug molecule linked to a polyethylene glycol group, and a method of u...
The presently-disclosed subject matter includes compounds including a cyclooxygenase enzyme inhibito...
The invention provides a novel method of administering narcotic antagonists, narcotic analgesics and...
The adequate treatment of pain remains one of the major medical challenges. Morphine and other opioi...
Patients with a history of abuse/misuse of pain and psychotic medications are at high risk for suici...
Putting into service a preliminary transdermal patch on the skin, an appropriate dosage of drug can ...
A pharmaceutical composition comprising a phosphatidylcholine-based opioid receptor antagonist formu...
Improved pharmacotherapies for opioid dependence treatment have become a necessity for maintaining i...
The invention provides compounds of formula I: wherein R1 to R4 and n have any of the meanings defin...
Particles comprising an opioid receptor antagonist as well as methods of their use and methods of th...
ABSTRACTOpioid continues as the main pharmacological treatment for severe acute pain. Extensive firs...
The present invention relates to the field of prodrugs of chemotherapeutic agents and method of use ...
The present invention relates to pharmaceutical compositions for intranasal administration to a mamm...
Novel compounds which selectively bind to the δ-opioid receptor have been designed. These compounds ...
Several investigations into the sites of action of opioid analgesics have utilized peripherally acti...
Prodrugs containing an active drug molecule linked to a polyethylene glycol group, and a method of u...
The presently-disclosed subject matter includes compounds including a cyclooxygenase enzyme inhibito...
The invention provides a novel method of administering narcotic antagonists, narcotic analgesics and...
The adequate treatment of pain remains one of the major medical challenges. Morphine and other opioi...
Patients with a history of abuse/misuse of pain and psychotic medications are at high risk for suici...
Putting into service a preliminary transdermal patch on the skin, an appropriate dosage of drug can ...