Add to ORKGThe present invention relates to the field of pain management, and more particularly to synergistic codrugs comprising an opioid and nornicotine which have been combined to form a single chemical codrug entity. When the codrug is administered it produces a synergistic analgesic response to pain
A codrug composition of at least two drug compounds covalently linked to one another via a labile bo...
Pain, although subjective, is an unpleasant sensation caused by a noxious stimulus, that effects mil...
The invention relates to a composition formed for anti-inflammatory and analgesic treatment and to t...
The present invention relates to the field of pain management, and more particularly to synergistic ...
The present invention relates to the field of pain management, and more particularly to synergistic ...
Pain is an unpleasant sensory and emotional experience associated with actual or potential tissus da...
Pain is the most common cause of medical consultations. Its treatment remains one of the biggest med...
The invention provides compounds of formula I: wherein R1 to R4 and n have any of the meanings defin...
Novel compounds which selectively bind to the δ-opioid receptor have been designed. These compounds ...
Novel compositions of a combination of nicotinic, opioid, serotonergic and/or adrenergic antagonists...
The authors review the opioid literature for evidence of increased analgesia and reduced adverse sid...
The current protocols for neuropathic pain management include µ-opioid receptor (MOR) analgesics alo...
Provided are methods for using bis-quaternary ammonium compounds to treat inflammatory pain, neuropa...
A codrug composition of at least two drug compounds covalently linked to one another via a labile bo...
Pain, although subjective, is an unpleasant sensation caused by a noxious stimulus, that effects mil...
The invention relates to a composition formed for anti-inflammatory and analgesic treatment and to t...
The present invention relates to the field of pain management, and more particularly to synergistic ...
The present invention relates to the field of pain management, and more particularly to synergistic ...
Pain is an unpleasant sensory and emotional experience associated with actual or potential tissus da...
Pain is the most common cause of medical consultations. Its treatment remains one of the biggest med...
The invention provides compounds of formula I: wherein R1 to R4 and n have any of the meanings defin...
Novel compounds which selectively bind to the δ-opioid receptor have been designed. These compounds ...
Novel compositions of a combination of nicotinic, opioid, serotonergic and/or adrenergic antagonists...
The authors review the opioid literature for evidence of increased analgesia and reduced adverse sid...
The current protocols for neuropathic pain management include µ-opioid receptor (MOR) analgesics alo...
Provided are methods for using bis-quaternary ammonium compounds to treat inflammatory pain, neuropa...
A codrug composition of at least two drug compounds covalently linked to one another via a labile bo...
Pain, although subjective, is an unpleasant sensation caused by a noxious stimulus, that effects mil...
The invention relates to a composition formed for anti-inflammatory and analgesic treatment and to t...