Add to ORKGProvided are bis-quaternary ammonium cyclophane compounds which are modulators of nicotinic acetylcholine receptors. Also provided are methods of using the compounds for modulating the function of a nicotinic acetylcholine receptor, and for the prevention and/or treatment of central nervous system disorders, substance use and/or abuse, and or gastrointestinal tract disorders
Neuronal nicotinic acetylcholine receptors (nAChRs) make up a family of pentameric ligand-gated ion ...
This document is the accepted manuscript version of a Published Work that appeared in final form in ...
Starting from a known non-specific agonist (1) of nicotinic acetylcholine receptors (nAChRs), ration...
Provided are bis-quaternary ammonium compounds which are modulators of nicotinic acetylcholine recep...
Provided are monoquaternary ammonium compounds which are modulators of nicotinic acetylcholine recep...
Provided are bis-quaternary ammonium compounds which are modulators of nicotinic acetylcholine recep...
Provided are tris-quaternary ammonium compounds which are modulators of nicotinic acetylocholine rec...
Provided are tetrakis-quaternary ammonium compounds which are modulators of nicotinic acetylcholine ...
N-n-Alkylation of nicotine converts nicotine from an agonist into an antagonist specifically for neu...
Compounds for treating abuse of nicotinic receptor agonists, addiction to psychostimulant drugs, add...
Pharmaceutical compounds comprising bridged nicotine analogs of N-octylnicotinium iodide (NONI) havi...
Provided are tris-quatemary ammonium compounds which are modulators of nociception and pain
Nicotine analogs that have nicotinic receptor antagonist properties. These compounds have been shown...
Compounds used for treating dependence on or withdrawal from a drug of abuse, for an eating disorder...
Nicotinic acetylcholine receptors (AChRs) are pentameric proteins that form agonist-gated cation cha...
Neuronal nicotinic acetylcholine receptors (nAChRs) make up a family of pentameric ligand-gated ion ...
This document is the accepted manuscript version of a Published Work that appeared in final form in ...
Starting from a known non-specific agonist (1) of nicotinic acetylcholine receptors (nAChRs), ration...
Provided are bis-quaternary ammonium compounds which are modulators of nicotinic acetylcholine recep...
Provided are monoquaternary ammonium compounds which are modulators of nicotinic acetylcholine recep...
Provided are bis-quaternary ammonium compounds which are modulators of nicotinic acetylcholine recep...
Provided are tris-quaternary ammonium compounds which are modulators of nicotinic acetylocholine rec...
Provided are tetrakis-quaternary ammonium compounds which are modulators of nicotinic acetylcholine ...
N-n-Alkylation of nicotine converts nicotine from an agonist into an antagonist specifically for neu...
Compounds for treating abuse of nicotinic receptor agonists, addiction to psychostimulant drugs, add...
Pharmaceutical compounds comprising bridged nicotine analogs of N-octylnicotinium iodide (NONI) havi...
Provided are tris-quatemary ammonium compounds which are modulators of nociception and pain
Nicotine analogs that have nicotinic receptor antagonist properties. These compounds have been shown...
Compounds used for treating dependence on or withdrawal from a drug of abuse, for an eating disorder...
Nicotinic acetylcholine receptors (AChRs) are pentameric proteins that form agonist-gated cation cha...
Neuronal nicotinic acetylcholine receptors (nAChRs) make up a family of pentameric ligand-gated ion ...
This document is the accepted manuscript version of a Published Work that appeared in final form in ...
Starting from a known non-specific agonist (1) of nicotinic acetylcholine receptors (nAChRs), ration...