Provided are bis-quaternary ammonium compounds which are modulators of nicotinic acetylcholine receptors. Also provided are methods of using the compounds for modulating the function of a nicotinic acetylcholine receptor, and for the prevention and/or treatment of central nervous system disorders, substance use and/or abuse, and or gastrointestinal tract disorders
This document is the accepted manuscript version of a Published Work that appeared in final form in ...
Provided are methods for using bis-quaternary ammonium compounds to treat inflammatory pain, neuropa...
Neuronal nicotinic acetylcholine receptors (nAChRs) make up a family of pentameric ligand-gated ion ...
Provided are bis-quaternary ammonium compounds which are modulators of nicotinic acetylcholine recep...
Provided are monoquaternary ammonium compounds which are modulators of nicotinic acetylcholine recep...
Provided are bis-quaternary ammonium cyclophane compounds which are modulators of nicotinic acetylch...
Provided are tetrakis-quaternary ammonium compounds which are modulators of nicotinic acetylcholine ...
Provided are tris-quaternary ammonium compounds which are modulators of nicotinic acetylocholine rec...
Provided are tris-quatemary ammonium compounds which are modulators of nociception and pain
N-n-Alkylation of nicotine converts nicotine from an agonist into an antagonist specifically for neu...
Nicotine analogs that have nicotinic receptor antagonist properties. These compounds have been shown...
Pharmaceutical compounds comprising bridged nicotine analogs of N-octylnicotinium iodide (NONI) havi...
Compounds for treating abuse of nicotinic receptor agonists, addiction to psychostimulant drugs, add...
This project utilized synthesis and in vitro assays to generate antagonist SARs at various nAChR sub...
Compounds used for treating dependence on or withdrawal from a drug of abuse, for an eating disorder...
This document is the accepted manuscript version of a Published Work that appeared in final form in ...
Provided are methods for using bis-quaternary ammonium compounds to treat inflammatory pain, neuropa...
Neuronal nicotinic acetylcholine receptors (nAChRs) make up a family of pentameric ligand-gated ion ...
Provided are bis-quaternary ammonium compounds which are modulators of nicotinic acetylcholine recep...
Provided are monoquaternary ammonium compounds which are modulators of nicotinic acetylcholine recep...
Provided are bis-quaternary ammonium cyclophane compounds which are modulators of nicotinic acetylch...
Provided are tetrakis-quaternary ammonium compounds which are modulators of nicotinic acetylcholine ...
Provided are tris-quaternary ammonium compounds which are modulators of nicotinic acetylocholine rec...
Provided are tris-quatemary ammonium compounds which are modulators of nociception and pain
N-n-Alkylation of nicotine converts nicotine from an agonist into an antagonist specifically for neu...
Nicotine analogs that have nicotinic receptor antagonist properties. These compounds have been shown...
Pharmaceutical compounds comprising bridged nicotine analogs of N-octylnicotinium iodide (NONI) havi...
Compounds for treating abuse of nicotinic receptor agonists, addiction to psychostimulant drugs, add...
This project utilized synthesis and in vitro assays to generate antagonist SARs at various nAChR sub...
Compounds used for treating dependence on or withdrawal from a drug of abuse, for an eating disorder...
This document is the accepted manuscript version of a Published Work that appeared in final form in ...
Provided are methods for using bis-quaternary ammonium compounds to treat inflammatory pain, neuropa...
Neuronal nicotinic acetylcholine receptors (nAChRs) make up a family of pentameric ligand-gated ion ...