Association of HLA-A alleles relation with HPV infection and cervical cancer

Author. Neringa Aleliūnienė. Title. Association of HLA-A alleles relation with HPV infection and cervical cancer. Work aim. To appreciate the relation between HLA-A alleles, HPV and cervical cancer. Tasks: 1. Identify HLA-A allele frequency in cervical cancer and healthy women. 2. Identify HLA-A alleles that increase and reduce the risk of cervical cancer. 3. Identify HLA-A allele association of HPV. Methods. For healthy and cervical cancer women was performed an oncocytological cervical smear test using liquid based method, detection of high risk genotypes of human papillomavirus and detection of human leukocyte antigen class A allele by a direct sequence-specific oligonucleotide method. Statistical analysis of the survey data was performed by IBM SPSS Statistics 20 program. The statistically significant difference is considered to be p