Glacier recession and the anticipation of spring snow melt driven by a warming climate could lead to changes in the hydrological cycle affecting not only the headwater catchments but also the areas downstream. In order to correctly predict the magnitude of future possible changes and to consider appropriate strategies of water management, a good understanding of the interaction between glaciers, climate and hydrology is needed. The aim of this study is to assess the effect of climate variability on the hydro-glaciological behaviour and its consequence on water availability in the Arve River catchment (French Alps) since 1960. It covers 1958 km2 and is composed by five nested catchments (Arveyron d’Argentière, Arveyron de la Mer de Glace, Ar...