The mammalian MyD88 signaling molecule participates in Toll receptor signaling within the cytoplasm. In this issue of Immunity, Marek and Kagan (2012) report that Drosophila (d)MyD88 acts instead at the plasma membrane to sort the signaling adaptor Tube
<p>Toll is activated by the processed Spätzle (left). Toll activation leads to intracellular signali...
International audienceThe Drosophila transmembrane receptor Toll plays a key role in specifying the ...
Summary Insects such as Drosophila rely entirely on innate immune responses to combat microbial path...
SummaryThe cell biological principles that govern innate immune responses in Drosophila are unknown....
The mammalian MyD88 signaling molecule participates in Toll receptor signaling within the cytoplasm....
Innate immunity mediated by Toll signalling has been extensively studied, but how Toll signalling is...
International audienceMyD88 is an adapter protein in the signal transduction pathway mediated by int...
International audienceWe report here the identification and functional characterization of DmMyD88, ...
<p>Upon binding activated (processed) Spätzle, Toll dimerizes. The resulting conformational change a...
The discovery of Toll in Drosophila and of the remarkable conservation in pathway composition and or...
Summary: Toll signaling is well known for its pivotal role in the host response against the invasion...
The MyD88 adapter protein links members of the toll-like receptor (TLR) and interleukin-1 receptor (...
SummaryBackgroundThe Drosophila Toll pathway takes part in both establishment of the embryonic dorso...
Toll and Toll-like receptors represent families of receptors involved in mediating innate immunity r...
Toll-like receptor (TLR) signaling is one of the most important signaling cascades of the innate imm...
<p>Toll is activated by the processed Spätzle (left). Toll activation leads to intracellular signali...
International audienceThe Drosophila transmembrane receptor Toll plays a key role in specifying the ...
Summary Insects such as Drosophila rely entirely on innate immune responses to combat microbial path...
SummaryThe cell biological principles that govern innate immune responses in Drosophila are unknown....
The mammalian MyD88 signaling molecule participates in Toll receptor signaling within the cytoplasm....
Innate immunity mediated by Toll signalling has been extensively studied, but how Toll signalling is...
International audienceMyD88 is an adapter protein in the signal transduction pathway mediated by int...
International audienceWe report here the identification and functional characterization of DmMyD88, ...
<p>Upon binding activated (processed) Spätzle, Toll dimerizes. The resulting conformational change a...
The discovery of Toll in Drosophila and of the remarkable conservation in pathway composition and or...
Summary: Toll signaling is well known for its pivotal role in the host response against the invasion...
The MyD88 adapter protein links members of the toll-like receptor (TLR) and interleukin-1 receptor (...
SummaryBackgroundThe Drosophila Toll pathway takes part in both establishment of the embryonic dorso...
Toll and Toll-like receptors represent families of receptors involved in mediating innate immunity r...
Toll-like receptor (TLR) signaling is one of the most important signaling cascades of the innate imm...
<p>Toll is activated by the processed Spätzle (left). Toll activation leads to intracellular signali...
International audienceThe Drosophila transmembrane receptor Toll plays a key role in specifying the ...
Summary Insects such as Drosophila rely entirely on innate immune responses to combat microbial path...
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