Addendum zu Brommethan (Methylbromid) [BAT Value Documentation in German language, 2016]

Brommethan (Methyl bromide): Addendum BAT value documentation (2016) The German Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area has re‐evaluated the “Biologischer Leitwert” (BLW) for methyl bromide, using bromide in serum/plasma to characterize the internal exposure. The critical effect of methyl bromide is a high acute and chronic neurotoxicity. It can pass through the skin so that biological monitoring is highly recommended. On the basis of results of a human study the occurrence of abnormal findings in the EEG is comparable for unexposed persons and persons with exposure to methyl bromide in concentrations below 12 mg bromide/l plasma. Thus the BLW value of 12 mg bromide/l plasma or serum was confirmed. The sampling time is at the end of exposure/shift after several previous shifts