Add to ORKGMany tumours, such as pancreas, lung and stomach cancers are not efficiently treated using current methodologies. New treatments are required which operate by previously unexplored mechanisms
More than 11 million people worldwide are diagnosed with cancer every year. New cancer drugs are req...
This dissertation details the chemistry work that has been done to support the Radu lab’s cancer res...
The new technology of combinational chemistry has been introduced to pharmaceutical companies, impro...
Although chemotherapy provides a potentially systemic cure for cancer, its application is hampered b...
Contains fulltext : 18595.pdf (publisher's version ) (Open Access)This thesis is d...
Charles University Faculty of Pharmacy in Hradec Králové Department of Organic and Bioorganic Chemis...
The effectiveness of current anticancer drugs such as nitrogen mustards, 5-fluorouracil and sunitini...
Bioreducible antitumour agents are prodrugs which are intended to be inactive in normal ceils, but a...
The concept of bioreductive prodrug chemotherapy is introduced in chapter 1. Tumour cell hypoxia is ...
This thesis describes the work conducted on three projects towards the development of putative inhib...
Cancer is a leading cause of death worldwide. Chemotherapy is the main approach used currently for t...
Our studies on the synthesis and biological evaluation of novel anticancer drugs consist of three re...
Includes bibliographical references (p. ).Cancer is the second leading cause of death in the United ...
Cancer is an increasing worldwide emergency, and its incidence and mortality will double in the next...
There is an urgent need to develop novel therapeutic strategies for common solid tumours including s...
More than 11 million people worldwide are diagnosed with cancer every year. New cancer drugs are req...
This dissertation details the chemistry work that has been done to support the Radu lab’s cancer res...
The new technology of combinational chemistry has been introduced to pharmaceutical companies, impro...
Although chemotherapy provides a potentially systemic cure for cancer, its application is hampered b...
Contains fulltext : 18595.pdf (publisher's version ) (Open Access)This thesis is d...
Charles University Faculty of Pharmacy in Hradec Králové Department of Organic and Bioorganic Chemis...
The effectiveness of current anticancer drugs such as nitrogen mustards, 5-fluorouracil and sunitini...
Bioreducible antitumour agents are prodrugs which are intended to be inactive in normal ceils, but a...
The concept of bioreductive prodrug chemotherapy is introduced in chapter 1. Tumour cell hypoxia is ...
This thesis describes the work conducted on three projects towards the development of putative inhib...
Cancer is a leading cause of death worldwide. Chemotherapy is the main approach used currently for t...
Our studies on the synthesis and biological evaluation of novel anticancer drugs consist of three re...
Includes bibliographical references (p. ).Cancer is the second leading cause of death in the United ...
Cancer is an increasing worldwide emergency, and its incidence and mortality will double in the next...
There is an urgent need to develop novel therapeutic strategies for common solid tumours including s...
More than 11 million people worldwide are diagnosed with cancer every year. New cancer drugs are req...
This dissertation details the chemistry work that has been done to support the Radu lab’s cancer res...
The new technology of combinational chemistry has been introduced to pharmaceutical companies, impro...