Structurally optimised BODIPY derivatives for imaging of mitochondrial dysfunction in cancer and heart cells
- Nigam, S.
- Burke, B.P.
- Davies, L.H.
- Domarkas, J.
- Wallis, J.F.
- Waddell, P.G.
- Waby, Jennifer S.
- Benoit, D.M.
- Seymour, A.-M.
- Cawthorne, C.
- Higham, L.J.
- Archibald, S.J.
DOIAbstract
YesThe structural features required for mitochondrial uptake of BODIPY-based optical imaging agents have been explored. The first derivatives of this class of dyes shown to have mitochondrial membrane potential-dependent uptake in both cancer and heart cells have been developed.Daisy Appeal Charity (Grant: DAhul0211), the University of Hull scholarship, Newcastle University, EPSRC and High Force Research Ltd, EPSRC Fellowship (EP/G005206/1
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