Add to ORKGSelective immunoglobulin A deficiency (SIgAD) is the most prevalent type of primary immunodeficiency disorder. The phenotypic feature of SIgAD is related to a defect in B lymphocyte differentiation into plasma cell-producing immunoglobulin A (IgA). In this review, we summarize the recent advances in this regard. Genetic (including major histocompatibility complex MHC and non-MHC genes), immunologic (including B and T lymphocyte subsets abnormality), cytokines/chemokines and their related receptors, apoptosis and microbiota defects are reviewed. The mechanisms leading to SIgAD are most likely multifactorial and it can be speculated that several pathways controlling B cells functions or regulating epigenetic of the IGHA gene encoding constant...
Selective immunoglobulin A deficiency (IgAD) is the most common primary immunodeficiency in Caucasia...
In recent years, the field of primary immunodeficienciency diseases (PID) has experienced remarkable...
Objectives: It has recently been shown that individuals with selective IgA deficiency (sIgAD) have d...
Selective immunoglobulin A deficiency (SIgAD) is the most prevalent type of primary immunodeficiency...
Objective Selective IgA deficiency (sIgAD) is the most common primary immunodeficiency in Western co...
Immunoglobulin A (IgA) deficiency is the most common primary immunodeficiency defined as decreased s...
Selective IgA deficiency (SIgAD), characterized by a serum IgA level below 0.07 mg/ml, while display...
Selective IgA deficiency (SIgAD) is the most common human primary immune deficiency (PID). It is cla...
Although selective IgM deficiency (SIGMD) was described almost five decades ago, it was largely igno...
SummaryImmunoglobulin A (IgA) deficiency (IgAD) is characterized by a defect of terminal lymphocyte ...
Objectives: It has recently been shown that individuals with selective IgA deficiency (sIgAD) have d...
University of Minnesota Ph.D. dissertation. September 2009. Major: Molecular, Cellular, Developmenta...
Introduction : Previous studies showed that several lymphocyte abnormalities seen in the most freque...
To access publisher's full text version of this article, please click on the hyperlink in Additional...
Primary selective IgM deficiency (SIGMD) is a rare and recently IUIS-recognized primary immunodefici...
Selective immunoglobulin A deficiency (IgAD) is the most common primary immunodeficiency in Caucasia...
In recent years, the field of primary immunodeficienciency diseases (PID) has experienced remarkable...
Objectives: It has recently been shown that individuals with selective IgA deficiency (sIgAD) have d...
Selective immunoglobulin A deficiency (SIgAD) is the most prevalent type of primary immunodeficiency...
Objective Selective IgA deficiency (sIgAD) is the most common primary immunodeficiency in Western co...
Immunoglobulin A (IgA) deficiency is the most common primary immunodeficiency defined as decreased s...
Selective IgA deficiency (SIgAD), characterized by a serum IgA level below 0.07 mg/ml, while display...
Selective IgA deficiency (SIgAD) is the most common human primary immune deficiency (PID). It is cla...
Although selective IgM deficiency (SIGMD) was described almost five decades ago, it was largely igno...
SummaryImmunoglobulin A (IgA) deficiency (IgAD) is characterized by a defect of terminal lymphocyte ...
Objectives: It has recently been shown that individuals with selective IgA deficiency (sIgAD) have d...
University of Minnesota Ph.D. dissertation. September 2009. Major: Molecular, Cellular, Developmenta...
Introduction : Previous studies showed that several lymphocyte abnormalities seen in the most freque...
To access publisher's full text version of this article, please click on the hyperlink in Additional...
Primary selective IgM deficiency (SIGMD) is a rare and recently IUIS-recognized primary immunodefici...
Selective immunoglobulin A deficiency (IgAD) is the most common primary immunodeficiency in Caucasia...
In recent years, the field of primary immunodeficienciency diseases (PID) has experienced remarkable...
Objectives: It has recently been shown that individuals with selective IgA deficiency (sIgAD) have d...