Background. Bacterial infections in the elderly are common and associated with high morbidity and mortality, with pneumonia the second commonest cause of death. Reductions in antibodies against specific bacterial antigens in saliva and serum could contribute to infection risk in older adults, although they have yet to be examined in relation to age. Method. IgG, IgA and IgM antibody levels in paired saliva and serum samples were measured against 12 pneumococcal, 4 meningococcal and haemophilus polysaccharide antigens and diphtheria and tetanus toxoids in healthy younger ( n = 28, 21–34 years) and older ( n = 44, 60–80 years) adults. Results. Older adults had lower antibody concentrations in saliva than young adults, with the most striking...
Producción CientíficaConcentrations of immunoglobulins (Ig) and levels of isotype specific antibodie...
Dessi Loukov,1,2,* Avee Naidoo,1,2,* Dawn ME Bowdish1,21Department of Pathology and Molecular Medici...
Older adults are at increased risk of pneumococcal disease. This work aims to evaluate whether there...
Background. Bacterial infections in the elderly are common and associated with high morbidity and mo...
Since the 23-valent pneumococcal polysaccharide vaccine (PPV23) is less effective for older adults t...
The incidence of community-acquired pneumonia and lower respiratory tract infection rises considerab...
Abstract Background The incidence of community-acquired pneumonia and lower respiratory tract infect...
Immunity against pneumococcal infections is impaired in older people, and current vaccines are poorl...
Abstract The worldwide increase in the aging population poses tough challenges to the health care co...
Introduction: Successful vaccination of elderly persons is often hampered by immunological ageing, l...
Abstract Background Streptococcus pneumoniae is a leading cause of morbidity and mortality in the el...
It is well known that older people are more susceptible to morbidity and mortality from infectious ...
Introduction: The major immunoglobulin present in mucosal secretions (e.g. saliva) is secretory immu...
The incidence of invasive pneumococcal disease (IPD) rises with age. Among adult IPD patients, the a...
The increase in the elderly population is impacting the social and economic aspects of the modern wo...
Producción CientíficaConcentrations of immunoglobulins (Ig) and levels of isotype specific antibodie...
Dessi Loukov,1,2,* Avee Naidoo,1,2,* Dawn ME Bowdish1,21Department of Pathology and Molecular Medici...
Older adults are at increased risk of pneumococcal disease. This work aims to evaluate whether there...
Background. Bacterial infections in the elderly are common and associated with high morbidity and mo...
Since the 23-valent pneumococcal polysaccharide vaccine (PPV23) is less effective for older adults t...
The incidence of community-acquired pneumonia and lower respiratory tract infection rises considerab...
Abstract Background The incidence of community-acquired pneumonia and lower respiratory tract infect...
Immunity against pneumococcal infections is impaired in older people, and current vaccines are poorl...
Abstract The worldwide increase in the aging population poses tough challenges to the health care co...
Introduction: Successful vaccination of elderly persons is often hampered by immunological ageing, l...
Abstract Background Streptococcus pneumoniae is a leading cause of morbidity and mortality in the el...
It is well known that older people are more susceptible to morbidity and mortality from infectious ...
Introduction: The major immunoglobulin present in mucosal secretions (e.g. saliva) is secretory immu...
The incidence of invasive pneumococcal disease (IPD) rises with age. Among adult IPD patients, the a...
The increase in the elderly population is impacting the social and economic aspects of the modern wo...
Producción CientíficaConcentrations of immunoglobulins (Ig) and levels of isotype specific antibodie...
Dessi Loukov,1,2,* Avee Naidoo,1,2,* Dawn ME Bowdish1,21Department of Pathology and Molecular Medici...
Older adults are at increased risk of pneumococcal disease. This work aims to evaluate whether there...