ABSTRACT Tetralone esters (4a–c) on hydroxy methylation with ethyl formate yielded 5a–c which on reduction with sodium borohydride followed by hydrolysis gave dihydroxy acid 8a–c. Base-catalysed cyclisation of 8a–c using p-toluene sulfonyl chloride gave β-apopicropodophyllin analogues (3a–c) in quantitative yield
The pyrazole analogues of podophyllotoxin were synthesized by the chalcone route. This route attract...
A novel synthesis of podophyllotoxin was carried out in four steps. The key step was reduction of is...
The new 3-ethyl carboxy-4-phenyl-6-fluoro-1-tetralone and 3-ethyl carboxy-4-(p-anisyl)-6-fluoro-1-te...
Analogues (5,6,7) of β - apopicropodophyllin 2 have been synthesized from tetralone acid intermedia...
3-Ethylcarboxy-4-trimethoxyphenyl-6,7-dimethyl-methylenedioxy-1- tetralone 5 and 3-ethyl carboxy-4-t...
1713-1720The benzodioxan analogue of didemethoxy- β-apopicropodophyllin 15 has been synthesized st...
The benzodioxan analogue of didemethoxy-beta-apopicropodophyllin 15 has been synthesized starting fr...
Tetralone acids 6, 7 and 8 have been synthesised as intermediates for, the synthesis of podophylloto...
274-277Preparation of tetralone ester 4a-c, an intermediate for the synthesis of β-apopicropodophy ...
Cyclopropyl ester (8a-f) were synthesized by the cyclopropanation of chalcones (7a-e) in dry benzene...
The indan analogue 4 of DL-tridemethoxy-beta-apopicropodophyllin 3 has been synthesized starting fro...
Furo 3',4' : 6,7]-naphtho 2,3-e]-1, 4-dioxin-7-one-6, 6a-tetrahydro-10-one-6-phenyl (9) and furo 3',...
Podophyllotoxin, one of the well-known naturally occurring lignan, has been used as the lead compoun...
New tetralone acid analogues of podophyllotoxin 7a-c i.e substituted 4-oxo-7-phenyl-4,5,6,7-tetrahyd...
A novel approach to (±)-epipodophyllotoxin (2) and hence also (±)-podophyllotoxin (1) is described, ...
The pyrazole analogues of podophyllotoxin were synthesized by the chalcone route. This route attract...
A novel synthesis of podophyllotoxin was carried out in four steps. The key step was reduction of is...
The new 3-ethyl carboxy-4-phenyl-6-fluoro-1-tetralone and 3-ethyl carboxy-4-(p-anisyl)-6-fluoro-1-te...
Analogues (5,6,7) of β - apopicropodophyllin 2 have been synthesized from tetralone acid intermedia...
3-Ethylcarboxy-4-trimethoxyphenyl-6,7-dimethyl-methylenedioxy-1- tetralone 5 and 3-ethyl carboxy-4-t...
1713-1720The benzodioxan analogue of didemethoxy- β-apopicropodophyllin 15 has been synthesized st...
The benzodioxan analogue of didemethoxy-beta-apopicropodophyllin 15 has been synthesized starting fr...
Tetralone acids 6, 7 and 8 have been synthesised as intermediates for, the synthesis of podophylloto...
274-277Preparation of tetralone ester 4a-c, an intermediate for the synthesis of β-apopicropodophy ...
Cyclopropyl ester (8a-f) were synthesized by the cyclopropanation of chalcones (7a-e) in dry benzene...
The indan analogue 4 of DL-tridemethoxy-beta-apopicropodophyllin 3 has been synthesized starting fro...
Furo 3',4' : 6,7]-naphtho 2,3-e]-1, 4-dioxin-7-one-6, 6a-tetrahydro-10-one-6-phenyl (9) and furo 3',...
Podophyllotoxin, one of the well-known naturally occurring lignan, has been used as the lead compoun...
New tetralone acid analogues of podophyllotoxin 7a-c i.e substituted 4-oxo-7-phenyl-4,5,6,7-tetrahyd...
A novel approach to (±)-epipodophyllotoxin (2) and hence also (±)-podophyllotoxin (1) is described, ...
The pyrazole analogues of podophyllotoxin were synthesized by the chalcone route. This route attract...
A novel synthesis of podophyllotoxin was carried out in four steps. The key step was reduction of is...
The new 3-ethyl carboxy-4-phenyl-6-fluoro-1-tetralone and 3-ethyl carboxy-4-(p-anisyl)-6-fluoro-1-te...