A novel synthesis of podophyllotoxin was carried out in four steps. The key step was reduction of isoxazoline ring followed by diazotization and the resultant alkene was treated with Mn(OAc)3/CH3COOK to form podophyllotoxin
Podophyllotoxin and its related lignans have been known andused in crude extracts for hundreds of ye...
A nickel-catalyzed reductive cascade approach to the efficient construction of diastereodivergent co...
A partir de la resina comercial (Podofilina) de Podophyllum emodi se aisló la podofilotoxina (1). Es...
Podophyllotoxin and its derivatives are well-studied and widely used in a broad range of therapeutic...
Bibliography: pages [52]-57.Podophyllotoxin is a molecule with interesting biological activity. Usin...
1713-1720The benzodioxan analogue of didemethoxy- β-apopicropodophyllin 15 has been synthesized st...
Analogues (5,6,7) of β - apopicropodophyllin 2 have been synthesized from tetralone acid intermedia...
3-Ethylcarboxy-4-trimethoxyphenyl-6,7-dimethyl-methylenedioxy-1- tetralone 5 and 3-ethyl carboxy-4-t...
A novel approach to (±)-epipodophyllotoxin (2) and hence also (±)-podophyllotoxin (1) is described, ...
ABSTRACT Tetralone esters (4a–c) on hydroxy methylation with ethyl formate yielded 5a–c which on red...
The benzodioxan analogue of didemethoxy-beta-apopicropodophyllin 15 has been synthesized starting fr...
The indan analogue 4 of DL-tridemethoxy-beta-apopicropodophyllin 3 has been synthesized starting fro...
Furo 3',4' : 6,7]-naphtho 2,3-e]-1, 4-dioxin-7-one-6, 6a-tetrahydro-10-one-6-phenyl (9) and furo 3',...
Since 1960, only seven plant-derived anticancer drugs have received FDA approval for commercial prod...
Cyclopropyl ester (8a-f) were synthesized by the cyclopropanation of chalcones (7a-e) in dry benzene...
Podophyllotoxin and its related lignans have been known andused in crude extracts for hundreds of ye...
A nickel-catalyzed reductive cascade approach to the efficient construction of diastereodivergent co...
A partir de la resina comercial (Podofilina) de Podophyllum emodi se aisló la podofilotoxina (1). Es...
Podophyllotoxin and its derivatives are well-studied and widely used in a broad range of therapeutic...
Bibliography: pages [52]-57.Podophyllotoxin is a molecule with interesting biological activity. Usin...
1713-1720The benzodioxan analogue of didemethoxy- β-apopicropodophyllin 15 has been synthesized st...
Analogues (5,6,7) of β - apopicropodophyllin 2 have been synthesized from tetralone acid intermedia...
3-Ethylcarboxy-4-trimethoxyphenyl-6,7-dimethyl-methylenedioxy-1- tetralone 5 and 3-ethyl carboxy-4-t...
A novel approach to (±)-epipodophyllotoxin (2) and hence also (±)-podophyllotoxin (1) is described, ...
ABSTRACT Tetralone esters (4a–c) on hydroxy methylation with ethyl formate yielded 5a–c which on red...
The benzodioxan analogue of didemethoxy-beta-apopicropodophyllin 15 has been synthesized starting fr...
The indan analogue 4 of DL-tridemethoxy-beta-apopicropodophyllin 3 has been synthesized starting fro...
Furo 3',4' : 6,7]-naphtho 2,3-e]-1, 4-dioxin-7-one-6, 6a-tetrahydro-10-one-6-phenyl (9) and furo 3',...
Since 1960, only seven plant-derived anticancer drugs have received FDA approval for commercial prod...
Cyclopropyl ester (8a-f) were synthesized by the cyclopropanation of chalcones (7a-e) in dry benzene...
Podophyllotoxin and its related lignans have been known andused in crude extracts for hundreds of ye...
A nickel-catalyzed reductive cascade approach to the efficient construction of diastereodivergent co...
A partir de la resina comercial (Podofilina) de Podophyllum emodi se aisló la podofilotoxina (1). Es...
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