Evaluation of in vitro antimicrobial activity of caesalpinia bonducella and cyclea peltata extracts against opportunistic microbes isolated from wounds in diabetic patients

Plants are known for treating infections since ancient times, they are a good source of having phytochemicals with marked antimicrobial activity against human pathogenic microorganisms. The present study was aimed for screening of phytochemicals and to determine antimicrobial potentials of Hexane, ethyl acetate and methanol extracts of Caesalpinia bonducella and Cyclea peltata against opportunistic microbes isolated from wounds in diabetic patients. Staphylococcus aureus, Pseudomonas aeruginosa, Streptococcus mutans, Proteus mirabilis, Escherichia coli and Candida albicans were identified in the diabetic patients wound infections. The plant extracts were screened for antimicrobial activity by agar disc diffusion method. Entire aerial part extracts of Cyclea peltata showed no zone of inhibition, however ethyl acetate leaf extract and methanolic root extract of Caesalpinia bonducella showed a moderate level of antimicrobial activity and their MIC were determined. Further research work is required in regarding isolation and characterization of active phytochemical compounds responsible for their antimicrobial activity