Add to ORKGA series of novel 2-methyl-3-(2-(piperazin-1-yl)ethyl)-6,7,8,9-tetrahydro-4H-pyrido1,2- a]pyrimidin-4-one sulfonamide and carboxamide derivatives were synthesized in good yield. The synthesized compounds were characterized by H-1-NMR, FTIR and elemental analysis. All the synthesised compounds were screened for their in vitro antimicrobial activity by agar well diffusion and micro dilution method against standard strains of Gram-positive (Bacillus subtilis MTCC 121, Staphylococcus epidermidis 435), and Gram-negative (Xanthomonas campestris 7903 and Pseudomonas aeruginosa MTCC 7908) bacteria. Compound 7a and compound 8d with dichloro substitution among sulphonamide and carboxamide series respectively showed potent inhibitory activity
Sulfonamide and Thio-pyrimidines derivatives are known for antibacterial activity and hence, in our ...
880-890The ethyl pyrido[2,3-h]quinolone carboxamides 7-31 have been synthesized and their ability ...
1-[2-(Aryl Amino-2-Oxo Ethyl) Amino]-4-(N-Methyl Piperazino)-Benzene Derivatives were synthesized. T...
A series of novel 3-(2-chloroethyl)-2-methyl-6,7,8,9-tetrahydro-4H- pyrido1,2-apyrimidin-4-one aliph...
A series of novel substituted 1-benzhydryl-piperazine sulfonamide 8(a–f) and benzamides 9(a–h) were ...
A series of novel substituted 2-[4-(2,4-dimethoxy-benzoyl)-phenoxy]-1-[4-(3-piperidin-4-yl-propyl)-p...
A series of new 2-methyl-3-(2-piperazin-1-yl-ethyl)-pyrido1,2-apyrimidin-4-one derivatives 6a-j were...
A series of new 2-(4-methylpiperazin-1-yl)-N-(4,6-diarylpyrimidin-2-yl)acetamides (34 – 42) have bee...
A series of new 2-(4-methylpiperazin-1-yl)-N-(4,6-diarylpyrimidin-2-yl)acetamides (34 – 42) have bee...
As a part of our quest for the synthesis of new bioactive heterocyclic compounds, in our present wor...
AbstractAs a part of our quest for the synthesis of new bioactive heterocyclic compounds, in our pre...
A series of novel heterocyclic hybrids, N-(4- (morpholine-4-carbonyl) thiazol-2-yl)-2-(piperazin-1-y...
A series of novel substituted 1-bis(4-fluorophenyl)-methylpiperazine derivatives (4a–g) and (5h–m) h...
A series of novel substituted 1-bis(4-fluorophenyl)-methylpiperazine derivatives (4a–g) and (5h–m) h...
Several 2-(5-chloro-3-methyl-1-(pyridin-2-yl) pyrazolidin-4-yl)-3- substitutedphenylthiazolidin-4-on...
Sulfonamide and Thio-pyrimidines derivatives are known for antibacterial activity and hence, in our ...
880-890The ethyl pyrido[2,3-h]quinolone carboxamides 7-31 have been synthesized and their ability ...
1-[2-(Aryl Amino-2-Oxo Ethyl) Amino]-4-(N-Methyl Piperazino)-Benzene Derivatives were synthesized. T...
A series of novel 3-(2-chloroethyl)-2-methyl-6,7,8,9-tetrahydro-4H- pyrido1,2-apyrimidin-4-one aliph...
A series of novel substituted 1-benzhydryl-piperazine sulfonamide 8(a–f) and benzamides 9(a–h) were ...
A series of novel substituted 2-[4-(2,4-dimethoxy-benzoyl)-phenoxy]-1-[4-(3-piperidin-4-yl-propyl)-p...
A series of new 2-methyl-3-(2-piperazin-1-yl-ethyl)-pyrido1,2-apyrimidin-4-one derivatives 6a-j were...
A series of new 2-(4-methylpiperazin-1-yl)-N-(4,6-diarylpyrimidin-2-yl)acetamides (34 – 42) have bee...
A series of new 2-(4-methylpiperazin-1-yl)-N-(4,6-diarylpyrimidin-2-yl)acetamides (34 – 42) have bee...
As a part of our quest for the synthesis of new bioactive heterocyclic compounds, in our present wor...
AbstractAs a part of our quest for the synthesis of new bioactive heterocyclic compounds, in our pre...
A series of novel heterocyclic hybrids, N-(4- (morpholine-4-carbonyl) thiazol-2-yl)-2-(piperazin-1-y...
A series of novel substituted 1-bis(4-fluorophenyl)-methylpiperazine derivatives (4a–g) and (5h–m) h...
A series of novel substituted 1-bis(4-fluorophenyl)-methylpiperazine derivatives (4a–g) and (5h–m) h...
Several 2-(5-chloro-3-methyl-1-(pyridin-2-yl) pyrazolidin-4-yl)-3- substitutedphenylthiazolidin-4-on...
Sulfonamide and Thio-pyrimidines derivatives are known for antibacterial activity and hence, in our ...
880-890The ethyl pyrido[2,3-h]quinolone carboxamides 7-31 have been synthesized and their ability ...
1-[2-(Aryl Amino-2-Oxo Ethyl) Amino]-4-(N-Methyl Piperazino)-Benzene Derivatives were synthesized. T...