Experimental data indicate that norepinephrine is critically involved in aspects of vigilance and attention. Previously, we considered the function of this neuromodulatory system on a time scale of minutes and longer, and suggested that it signals global uncertainty arising from gross changes in environmental contingencies. However, norepinephrine is also known to be activated phasically by familiar stimuli in well-learned tasks. Here, we extend our uncertainty-based treatment of norepinephrine to this phasic mode, proposing that it is involved in the detection and reaction to state uncertainty within a task. This role of norepinephrine can be understood through the metaphor of neural interrupts
Inference and adaptation in noisy and changing, rich sensory environ-ments are rife with a variety o...
Inference and adaptation in noisy and changing, rich sensory environments are rife with a variety of...
Although consciousness can be brought to bear on both perceptual and internally generated informatio...
Experimental data indicate that norepinephrine is critically involved in aspects of vigilance and at...
Experimental data indicate that norepinephrine is critically involved in aspects of vigilance and at...
Extensive animal studies indicate that the neuromodulator norepinephrine plays an important role in ...
The ability to track the statistics of our surroundings is a key computational challenge. A prominen...
SummaryUncertainty in various forms plagues our interactions with the environment. In a Bayesian sta...
Uncertainty in various forms plagues our interactions with the environment. In a Bayesian statistica...
The ability to track the statistics of our surroundings is a key computational challenge. A prominen...
A rich body of experimental data indicates that the neuromodulatory systems acetylcholine (ACh) and ...
Uncertainty in various forms plagues our interactions with the environment. In a Bayesian statistica...
Uncertainty in various forms plagues our interactions with the environment. In a Bayesian statistica...
Successful interaction with the environment requires flexible updating of our beliefs about the worl...
Successful interaction with the environment requires flexible updating of our beliefs about the worl...
Inference and adaptation in noisy and changing, rich sensory environ-ments are rife with a variety o...
Inference and adaptation in noisy and changing, rich sensory environments are rife with a variety of...
Although consciousness can be brought to bear on both perceptual and internally generated informatio...
Experimental data indicate that norepinephrine is critically involved in aspects of vigilance and at...
Experimental data indicate that norepinephrine is critically involved in aspects of vigilance and at...
Extensive animal studies indicate that the neuromodulator norepinephrine plays an important role in ...
The ability to track the statistics of our surroundings is a key computational challenge. A prominen...
SummaryUncertainty in various forms plagues our interactions with the environment. In a Bayesian sta...
Uncertainty in various forms plagues our interactions with the environment. In a Bayesian statistica...
The ability to track the statistics of our surroundings is a key computational challenge. A prominen...
A rich body of experimental data indicates that the neuromodulatory systems acetylcholine (ACh) and ...
Uncertainty in various forms plagues our interactions with the environment. In a Bayesian statistica...
Uncertainty in various forms plagues our interactions with the environment. In a Bayesian statistica...
Successful interaction with the environment requires flexible updating of our beliefs about the worl...
Successful interaction with the environment requires flexible updating of our beliefs about the worl...
Inference and adaptation in noisy and changing, rich sensory environ-ments are rife with a variety o...
Inference and adaptation in noisy and changing, rich sensory environments are rife with a variety of...
Although consciousness can be brought to bear on both perceptual and internally generated informatio...