Add to ORKGThere has been extensive research regarding T cell recognition of Epstein-Barr virus-transformed cells; however, less is known regarding the recognition of B cells immortalized by gamma-2 herpesviruses. Here we show that B cells immortalized by murine gammaherpesvirus 68 (MHV-68, γHV-68) can be controlled by either CD4 or CD8 T cells in vivo. We present evidence for the direct recognition of infected B cells by CD4 and CD8 T cells. These data will help in the development of immunotherapeutic approaches combating gamma-2 herpesvirus-related disease
The interactions between CD80 and CD86 on antigen-presenting cells and CD28 on T cells serve as an i...
Human gammaherpesviruses are associated with the development of lymphoproliferative diseases and B c...
<div><p>The human gammaherpesviruses establish life-long infections that are associated with the dev...
There has been extensive research regarding T cell recognition of Epstein-Barr virus-transformed cel...
Murine gammaherpesvirus 68 (MHV-68) is a natural pathogen of murid rodents and is closely related to...
CD8 T cells are potent immune effector cells capable of vast clonal expansion and clearance of infec...
Vaccination against gamma-herpesviruses has been hampered by our limited understanding of their norm...
SummaryTo study the CD8+ T cell response against a mouse γ-herpes virus, we generated Kb-MHV-68-ORF8...
The murine γ-herpesvirus 68 (MHV-68) provides a unique experimental model for dissecting immunity to...
Control of virus infection is mediated in part by major histocompatibility complex (MHC) Class Ia pr...
In herpesvirus infections, the virus persists for life but is contained through T-cell-mediated immu...
AbstractMurine gammaherpesvirus 68 (γHV68, MHV-68)-specific CD4 T cells control γHV68 infection by r...
A unique experimental model has been developed for dissecting the integrity of CD8+ T cell-mediated ...
CD4 T cells are important for control of infection with murine gammaherpesvirus 68 (HV68), but it is...
Epstein-Barr virus (EBV) is associated with a spectrum of benign and malignant lymphoproliferative d...
The interactions between CD80 and CD86 on antigen-presenting cells and CD28 on T cells serve as an i...
Human gammaherpesviruses are associated with the development of lymphoproliferative diseases and B c...
<div><p>The human gammaherpesviruses establish life-long infections that are associated with the dev...
There has been extensive research regarding T cell recognition of Epstein-Barr virus-transformed cel...
Murine gammaherpesvirus 68 (MHV-68) is a natural pathogen of murid rodents and is closely related to...
CD8 T cells are potent immune effector cells capable of vast clonal expansion and clearance of infec...
Vaccination against gamma-herpesviruses has been hampered by our limited understanding of their norm...
SummaryTo study the CD8+ T cell response against a mouse γ-herpes virus, we generated Kb-MHV-68-ORF8...
The murine γ-herpesvirus 68 (MHV-68) provides a unique experimental model for dissecting immunity to...
Control of virus infection is mediated in part by major histocompatibility complex (MHC) Class Ia pr...
In herpesvirus infections, the virus persists for life but is contained through T-cell-mediated immu...
AbstractMurine gammaherpesvirus 68 (γHV68, MHV-68)-specific CD4 T cells control γHV68 infection by r...
A unique experimental model has been developed for dissecting the integrity of CD8+ T cell-mediated ...
CD4 T cells are important for control of infection with murine gammaherpesvirus 68 (HV68), but it is...
Epstein-Barr virus (EBV) is associated with a spectrum of benign and malignant lymphoproliferative d...
The interactions between CD80 and CD86 on antigen-presenting cells and CD28 on T cells serve as an i...
Human gammaherpesviruses are associated with the development of lymphoproliferative diseases and B c...
<div><p>The human gammaherpesviruses establish life-long infections that are associated with the dev...