The Anti-hyperuricemic Effect of Torbangun (Coleus amboinicus Lour) Aqueous Extract

The study aimed to analyze the effect of Torbangun to reduction uric acid in woman with hypercholesterolemia. Design experiment used in this study was pre and post test controlled group design. The first step of this study was analyzed bioactive compound of torbangun aqueous extract. The next step was administired orally of Torbangun extract to control and woman with hypercholesterolemia for 30 days, with 30 subjects placed in two groups, viz, experimental (CC group) and placebo (PC group). The first group received one capsules of CC (each capsule contains 500 mg extract) while the second group received one capsules of PC (comprised of 500 mg fillers) one times daily for both groups. Uric acid (UA) and total cholesterol (TC) were measured in the first and the end of intervention. Oral administired of Torbangun extract exhibited reduce of hyper uric acid and hyper total cholesterol in woman with hypercholesterolemia. Data were analyzed with paired sample t test with 95% significance level. The results show that there was significant decrease in UA and TC on day 30, compared to control (PC group). In CC group, the capsules significant reduction in UA levels (p=0.001) and TC levels (p=0.000). Studies clearly demonstrated that Torbangun (Coleus amboinicus Lour) aqueous extract possesses antihyperuricemic activity in woman with hypercholesterolemia. Index Terms- uric acid, antihyperuricemic, torbangun extrac